Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage
degradation but also synovial membrane inflammation, osteophyte formation and …

Articular hyaline cartilage is extensively hydrated, but it is neither innervated nor
vascularized, and its low cell density allows only extremely limited self-renewal. Most clinical …

One of the most important issues facing cartilage tissue engineering is the inability to move
technologies into the clinic. Despite the multitude of current research in the field, it is known …

The cartilaginous endplates (CEP) are key components of the intervertebral disc (IVD)
necessary for sustaining the nutrition of the disc while distributing mechanical loads and …

The joints of mammals are lined with cartilage, comprised of individual chondrocytes
embedded in a specialized extracellular matrix. Chondrocytes experience a complex …

Extrusion-based bioprinting (EBB) is a rapidly develo** technique that has made
substantial progress in the fabrication of constructs for cartilage tissue engineering (CTE) …

Articular cartilage damage is a universal health problem. Despite recent progress,
chondrocyte dedifferentiation has severely compromised the clinical outcomes of cell-based …

Cartilage is mainly composed of chondrocytes and the extracellular matrix (ECM), which
transmits important biochemical and biomechanical signals necessary for differentiation and …

In situ tissue regeneration using cell‐free biofunctional scaffolds has been extensively
studied as a promising alternative strategy to promote cartilage repair. In this study, a …

Introduction This study aimed to evaluate whether profiles of several soluble mediators in
synovial fluid and cartilage tissue are pathology-dependent and how their production is …