Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's disease
E Blázquez, E Velázquez… - Frontiers in …, 2014 - frontiersin.org
Although the brain has been considered an insulin-insensitive organ, recent reports on the
location of insulin and its receptors in the brain have introduced new ways of considering …
location of insulin and its receptors in the brain have introduced new ways of considering …
a comparison of glucagon‐like peptides 1 and 2
P Janssen, A Rotondo, F Mulé… - Alimentary pharmacology …, 2013 - Wiley Online Library
Background Recent advancements in understanding the roles and functions of glucagon‐
like peptide 1 (GLP‐1) and 2 (GLP‐2) have provided a basis for targeting these peptides in …
like peptide 1 (GLP‐1) and 2 (GLP‐2) have provided a basis for targeting these peptides in …
Glucagon-like peptide 2 induces vasoactive intestinal polypeptide expression in enteric neurons via phophatidylinositol 3-kinase-γ signaling
E de Heuvel, L Wallace, KA Sharkey… - American Journal of …, 2012 - journals.physiology.org
Glucagon-like peptide 2 (GLP-2) is an enteroendocrine hormone trophic for intestinal
mucosa; it has been shown to increase enteric neuronal expression of vasoactive intestinal …
mucosa; it has been shown to increase enteric neuronal expression of vasoactive intestinal …
GLP-2 dysregulates hepatic lipoprotein metabolism, inducing fatty liver and VLDL overproduction in male hamsters and mice
J Taher, C Baker, D Alvares, L Ijaz, M Hussain… - …, 2018 - academic.oup.com
Fundamental complications of insulin resistance and type 2 diabetes include the
development of nonalcoholic fatty liver disease and an atherogenic fasting dyslipidemic …
development of nonalcoholic fatty liver disease and an atherogenic fasting dyslipidemic …
GLP‐2 receptor expression in excitatory and inhibitory enteric neurons and its role in mouse duodenum contractility
L Cinci, MS Faussone‐Pellegrini… - …, 2011 - Wiley Online Library
Background Glucagon‐like peptide 2 (GLP‐2), a nutrient‐responsive hormone, exerts
various actions in the gastrointestinal tract that are mediated by a G‐protein coupled …
various actions in the gastrointestinal tract that are mediated by a G‐protein coupled …
Glucagon-like peptide-2 but not imipramine exhibits antidepressant-like effects in ACTH-treated mice
We investigated the effectiveness of glucagon-like peptide-2 (GLP-2) against refractory
depression in adrenocorticotropic hormone (ACTH)-treated mice as a model of tricyclic …
depression in adrenocorticotropic hormone (ACTH)-treated mice as a model of tricyclic …
Peptide discovery across the spectrum of neuroinflammation; microglia and astrocyte phenotypical targeting, mediation, and mechanistic understanding
BA Benita, KM Koss - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Uncontrolled and chronic inflammatory states in the Central Nervous System (CNS) are the
hallmark of neurodegenerative pathology and every injury or stroke-related insult. The key …
hallmark of neurodegenerative pathology and every injury or stroke-related insult. The key …
Glucagon-like peptide 2 in colon carcinogenesis: Possible target for anti-cancer therapy?
The role of glucagon-like peptide 2 (GLP2) in colon tissue has been studied extensively,
from the time it was discovered that GLP2 promotes intestinal growth. A large number of …
from the time it was discovered that GLP2 promotes intestinal growth. A large number of …
Glucagon-like peptide-2-induced memory improvement and anxiolytic effects in mice
We investigated the effectiveness of glucagon-like peptide-2 (GLP-2) on memory impairment
in lipopolysaccharide (LPS)-treated mice, and anxiety-like behavior in adrenocorticotropic …
in lipopolysaccharide (LPS)-treated mice, and anxiety-like behavior in adrenocorticotropic …
[LIVRE][B] Гормональные системы мозга и сахарный диабет 2-го типа
АО Шпаков, КВ Деркач - 2015 - elibrary.ru
В монографии впервые рассмотрена роль изменений в сигнальных системах мозга,
регулируемых инсулином, инсулиноподобным фактором роста-1, лептином, пептидами …
регулируемых инсулином, инсулиноподобным фактором роста-1, лептином, пептидами …