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[HTML][HTML] Alternatively spliced isoforms of the P2X7 receptor: structure, function and disease associations
SKF De Salis, L Li, Z Chen, KW Lam… - International Journal of …, 2022 - mdpi.com
The P2X7 receptor (P2X7R) is an ATP-gated membrane ion channel that is expressed by
multiple cell types. Following activation by extracellular ATP, the P2X7R mediates a broad …
multiple cell types. Following activation by extracellular ATP, the P2X7R mediates a broad …
[HTML][HTML] The catastrophic HPV/HIV dual viral oncogenomics in concert with dysregulated alternative splicing in cervical cancer
Cervical cancer is a public health problem and has devastating effects in low-to-middle-
income countries (LTMICs) such as the sub-Saharan African (SSA) countries. Infection by …
income countries (LTMICs) such as the sub-Saharan African (SSA) countries. Infection by …
RNPS1 functions as an oncogenic splicing factor in cervical cancer cells
Numerous recent studies suggest that cancer‐specific splicing alteration is a critical
contributor to the pathogenesis of cancer. RNA‐binding protein with serine‐rich domain 1 …
contributor to the pathogenesis of cancer. RNA‐binding protein with serine‐rich domain 1 …
LncRNA ABHD11-AS1 activates EGFR signaling to promote cervical cancer progression by preventing FUS-mediated degradation of ABHD11 mRNA
T Yang, S Tian, J Zhao, M Pei, M Zhao, X Yang - Cell Cycle, 2023 - Taylor & Francis
Cervical cancer is one of the most common gynecological cancers with high metastasis,
poor prognosis and conventional chemotherapy. The long non-coding RNA (lncRNA) …
poor prognosis and conventional chemotherapy. The long non-coding RNA (lncRNA) …
Diverse roles of heterogeneous nuclear ribonucleoproteins in viral life cycle
Understanding the host-virus interactions helps to decipher the viral replication strategies
and pathogenesis. Viruses have limited genetic content and rely significantly on their host …
and pathogenesis. Viruses have limited genetic content and rely significantly on their host …
Everolimus (RAD001) combined with programmed death-1 (PD-1) blockade enhances radiosensitivity of cervical cancer and programmed death-ligand 1 (PD-L1) …
L Song, S Liu, S Zhao - Bioengineered, 2022 - Taylor & Francis
Cervical cancer (CC) is the 4th most prevalent malignancy in females. This study explored
the mechanism of everolimus (RAD001) combined with programmed death-1 (PD-1) …
the mechanism of everolimus (RAD001) combined with programmed death-1 (PD-1) …
Foxo3a-mediated DNMT3B impedes cervical cancer cell proliferation and migration capacities through suppressing PTEN promoter methylation
H Li, Y Yuan, H Dong, T Wang, D Zhang… - Journal of …, 2023 - Taylor & Francis
Objective Cervical cancer is linked with the constitutive activation of growth factors and gene
mutations-induced pro-survival signaling pathways. Herein, we purposed to explore the …
mutations-induced pro-survival signaling pathways. Herein, we purposed to explore the …
TXNL4B regulates radioresistance by controlling the PRP3‐mediated alternative splicing of FANCI
Z Ju, J **ang, L **ao, Y He, L Zhang, Y Wang… - MedComm, 2023 - Wiley Online Library
Ionizing radiation (IR) has been extensively used for cancer therapy, but the radioresistance
hinders and undermines the radiotherapy efficacy in clinics greatly. Here, we reported that …
hinders and undermines the radiotherapy efficacy in clinics greatly. Here, we reported that …
Pro-apoptotic and anti-apoptotic regulation mediated by deubiquitinating enzymes
HS Choi, KH Baek - Cellular and Molecular Life Sciences, 2022 - Springer
Although damaged cells can be repaired, cells that are considered unlikely to be repaired
are eliminated through apoptosis, a type of predicted cell death found in multicellular …
are eliminated through apoptosis, a type of predicted cell death found in multicellular …
The exon 12‐containing LHX6 isoforms promote cervical cancer cell proliferation by regulating the MAPK signaling pathway
L Wang, Y Zhou, C Cao, S Lin, W Zhi, D Zhang… - Cancer …, 2022 - Wiley Online Library
Abstract LIM homeobox 6 (LHX6) has been reported to be downregulated and inhibits cell
proliferation in various cancers. Alternative splicing of LHX6 leads to six annotated isoforms …
proliferation in various cancers. Alternative splicing of LHX6 leads to six annotated isoforms …