Basic principles of photodynamic therapy

IJ Macdonald, TJ Dougherty - Journal of porphyrins and …, 2001 - World Scientific
The therapeutic use of light, as we know it, begins in 1900 when Raab reported that the
combination of acridine orange and light could destroy living organisms (paramecium)[1]. In …

[HTML][HTML] State of the art in the delivery of photosensitizers for photodynamic therapy

YN Konan, R Gurny, E Allémann - Journal of Photochemistry and …, 2002 - Elsevier
In photodynamic therapy, one of the problems limiting the use of many photosensitizers (PS)
is the difficulty in preparing pharmaceutical formulations that enable their parenteral …

Targeted photodynamic therapy via receptor mediated delivery systems

WM Sharman, JE van Lier, CM Allen - Advanced drug delivery reviews, 2004 - Elsevier
Targeted photodynamic therapy (PDT) offers the opportunity of enhancing photodynamic
efficiency by directly targeting diseased cells and tissues. While antibody-conjugates have …

Vascular and cellular targeting for photodynamic therapy

B Chen, BW Pogue, PJ Hoopes… - Critical Reviews™ in …, 2006 - dl.begellhouse.com
Photodynamic therapy (PDT) involves the combination of photosensitizers (PS) with light as
a treatment, and has been an established medical practice for about 10 years. Current …

Acidity‐triggered tumor‐targeted chimeric peptide for enhanced intra‐nuclear photodynamic therapy

K Han, WY Zhang, J Zhang, Q Lei… - Advanced Functional …, 2016 - Wiley Online Library
Photodynamic therapy suffers from poor tumor selectivity and poor therapeutical efficacy. In
this paper, an amphiphilic chimeric peptide is fabricated to realize sequential acidity …

Photosensitizer-antibody conjugates for detection and therapy of cancer

G Van Dongen, GWM Visser… - Advanced drug delivery …, 2004 - Elsevier
Photodynamic therapy (PDT) is a promising approach for the treatment of superficially
localized tumors. A limitation, however, is the lack of selectivity of the photosensitizers, which …

Photodynamic therapy: a review

JS McCaughan - Drugs & aging, 1999 - Springer
Photodynamic therapy (PDT) of malignant tumours is a new technique for treating cancers.
After intravenous injection, a photosensitiser is selectively retained by the tumour cells so …

Near‐infrared absorbing polymeric nanoparticles as a versatile drug carrier for cancer combination therapy

H Gong, L Cheng, J **ang, H Xu… - Advanced Functional …, 2013 - Wiley Online Library
Abstract Poly (3, 4‐ethylenedioxythiophene): poly (4‐styrenesulfonate)(PEDOT: PSS)
nanoparticles, after being coated with polyethylene glycol (PEG), are used as a drug carrier …

Intranuclear photosensitizer delivery and photosensitization for enhanced photodynamic therapy with ultralow irradiance

L Pan, J Liu, J Shi - Advanced Functional Materials, 2014 - Wiley Online Library
Photodynamic therapy (PDT) is a well‐established clinical treatment modality for various
diseases. However, reactive oxygen species (ROS) generated by photosensitizers (PS) …

[HTML][HTML] Toward understanding the high PDT efficacy of chlorin e6–polyvinylpyrrolidone formulations: Photophysical and molecular aspects of photosensitizer …

HA Isakau, MV Parkhats, VN Knyukshto… - … of Photochemistry and …, 2008 - Elsevier
It is recognized that chlorin e6–polyvinylpyrrolidone (Ce6–PVP) formulations are
characterized by a high efficacy in photodynamic therapy of malignant tumors. Currently, a …