Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Oils and fats of vegetable and animal origin remain an important renewable feedstock for the
chemical industry. Their industrial use has increased during the last 10 years from 31 to 51 …

As the enzyme toolbox for biocatalysis has expanded, so has the potential for the
construction of powerful enzymatic cascades for efficient and selective synthesis of target …

The pharmaceutical industry, driven by an increasing need to deliver new and more effective
medicines to patients, is increasingly turning to the use of engineered biocatalysts for both …

The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

Photoexcitation is a common strategy for initiating radical reactions in chemical synthesis.
We found that photoexcitation of flavin-dependent “ene”-reductases changes their catalytic …

Transaminases (TAs) are one of the most promising biocatalysts in organic synthesis for the
preparation of chiral amino compounds. The concise reaction, excellent enantioselectivity …

Chiral amines are pivotal building blocks for the pharmaceutical industry. Asymmetric
reductive amination is one of the most efficient and atom economic methodologies for the …

Transaminases have attracted considerable interest in their use as biocatalysts for the
synthesis of compounds containing chiral amine units, which are widespread within the …

The combination of sequential biocatalytic reactions, via non-natural synthetic cascades, is a
rapidly develo** field and leads to the generation of complex valuable chemicals from …