C–H activation has emerged as a viable alternative to traditional C–C bond forming
reactions such as the Suzuki–Miyaura, Stille, Negishi and others. However, C–H activation …

A novel series of substituted 4, 6-dimethyl-2-oxo-1-(thiazol-2-ylamino)-1, 2-dihydropyridine-
3-carbonitrile derivatives 6, 9, 13, 15, and 17 was synthesized in a good to excellent yield …

Abstract Pyrimido [4, 5-b] quinoline is a vital structural motif. The synthesis of pyrimido [4, 5-
b] quinolines has been a challenging topic in medicinal chemistry. A wide range of starting …

Microbial DNA gyrase is regarded as an outstanding microbial target. Hence, 15 new
quinoline derivatives (5–14) were designed and synthesized. The antimicrobial activity of …

Citrus reticulata dropped fruits are generally discarded as waste, causing environmental
pollution and losses to farmers. In the present study, column chromatography has been used …

The possibility of tracing the botanical and geographical origin of products such as honey
has become more important because of market globalization. As a consequence, numerous …

An iridium complex successfully catalyzed the annulation of various N-arylcarbamoyl
chlorides with internal alkynes to afford 2-quinolones in good to excellent yields. The …

Quinolones continue to receive significant attention owing to their diverse range of biological
activities. They provide an important scaffold in anticancer, antibacterial and antiviral drug …

Abstract The quinazolin-4 (3H)-one structural motif possesses a wide spectrum of biological
activities. DNA gyrase play an important role in induction of bacterial death. It has been …

A series of novel 4-anilinoquinazoline derivatives were designed and synthesized from
benzoic acid through ring closure, chlorination or nucleophilic substitution. The structures of …