The gut microbiota in inflammatory bowel disease

P Qiu, T Ishimoto, L Fu, J Zhang, Z Zhang… - Frontiers in cellular and …, 2022‏ - frontiersin.org
Epidemiological surveys indicate that the incidence of inflammatory bowel disease (IBD) is
increasing rapidly with the continuous growth of the economy. A large number of studies …

The metabolic nature of inflammatory bowel diseases

TE Adolph, M Meyer, J Schwärzler, L Mayr… - Nature Reviews …, 2022‏ - nature.com
Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …

[HTML][HTML] Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

S Federici, S Kredo-Russo, R Valdés-Mas… - Cell, 2022‏ - cell.com
Human gut commensals are increasingly suggested to impact non-communicable diseases,
such as inflammatory bowel diseases (IBD), yet their targeted suppression remains a …

Crosstalk between gut microbiota and host immunity: impact on inflammation and immunotherapy

C Campbell, MR Kandalgaonkar, RM Golonka… - Biomedicines, 2023‏ - mdpi.com
Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

Gut dysbiosis: Ecological causes and causative effects on human disease

SE Winter, AJ Bäumler - Proceedings of the National Academy of …, 2023‏ - pnas.org
The gut microbiota plays a role in many human diseases, but high-throughput sequence
analysis does not provide a straightforward path for defining healthy microbial communities …

Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders

A Metwaly, S Reitmeier, D Haller - Nature reviews Gastroenterology & …, 2022‏ - nature.com
The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020‏ - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

[HTML][HTML] Role and mechanism of gut microbiota in human disease

Y Chen, J Zhou, L Wang - Frontiers in cellular and infection …, 2021‏ - frontiersin.org
The human gut microbiome is a huge microbial community that plays an irreplaceable role
in human life. With the further development of research, the influence of intestinal flora on …

The microbiome and inflammatory bowel disease

KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020‏ - Elsevier
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …

Host–microbiota interactions in inflammatory bowel disease

R Caruso, BC Lo, G Núñez - Nature Reviews Immunology, 2020‏ - nature.com
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …