Lipid droplets in the nervous system
Lipid droplets are dynamic intracellular lipid storage organelles that respond to the
physiological state of cells. In addition to controlling cell metabolism, they play a protective …
physiological state of cells. In addition to controlling cell metabolism, they play a protective …
Are reactive oxygen species always detrimental to pathogens?
Reactive oxygen species (ROS) are deadly weapons used by phagocytes and other cell
types, such as lung epithelial cells, against pathogens. ROS can kill pathogens directly by …
types, such as lung epithelial cells, against pathogens. ROS can kill pathogens directly by …
Phenotypic and functional characterization of first-trimester human placental macrophages, Hofbauer cells
Hofbauer cells (HBCs) are a population of macrophages found in high abundance within the
stroma of the first-trimester human placenta. HBCs are the only fetal immune cell population …
stroma of the first-trimester human placenta. HBCs are the only fetal immune cell population …
Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer
Cross-presentation is a critical function of dendritic cells (DCs) required for induction of
antitumor immune responses and success of cancer immunotherapy. It is established that …
antitumor immune responses and success of cancer immunotherapy. It is established that …
Lipid droplets and lipid mediators in viral infection and immunity
Lipid droplets (LDs) contribute to key pathways important for the physiology and
pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids …
pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids …
Lipid droplets and polyunsaturated fatty acid trafficking: Balancing life and death
M Danielli, L Perne, E Jarc Jovičić… - Frontiers in Cell and …, 2023 - frontiersin.org
Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …
Lipid droplets as immune modulators in myeloid cells
MH den Brok, TK Raaijmakers, E Collado-Camps… - Trends in …, 2018 - cell.com
Lipid droplets (LDs) were initially described as fat storage organelles in adipocytes, but are
increasingly recognized as dynamic players in lipid metabolism, with important roles not …
increasingly recognized as dynamic players in lipid metabolism, with important roles not …
Foam cells: one size doesn't fit all
V Guerrini, ML Gennaro - Trends in immunology, 2019 - cell.com
Chronic inflammation in many infectious and metabolic diseases, and some cancers, is
accompanied by the presence of foam cells. These cells form when the intracellular lipid …
accompanied by the presence of foam cells. These cells form when the intracellular lipid …
Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response
Lipid droplets (LDs) are increasingly recognized as critical organelles in signalling events,
transient protein sequestration and inter-organelle interactions. However, the role LDs play …
transient protein sequestration and inter-organelle interactions. However, the role LDs play …
Host lipid droplets: An important source of lipids salvaged by the intracellular parasite Toxoplasma gondii
SJ Nolan, JD Romano, I Coppens - PLoS pathogens, 2017 - journals.plos.org
Toxoplasma is an obligate intracellular parasite that replicates in mammalian cells within a
parasitophorous vacuole (PV) that does not fuse with any host organelles. One mechanism …
parasitophorous vacuole (PV) that does not fuse with any host organelles. One mechanism …