[HTML][HTML] Lipocalin-2: Structure, function, distribution and role in metabolic disorders

S Al Jaberi, A Cohen, C D'Souza… - Biomedicine & …, 2021 - Elsevier
Abstract Lipocalin-2 (LCN-2) is a novel, 198 amino acid adipocytokine also referred to as
neutrophil gelatinase-associated lipocalin (NGAL). LCN-2 is a circulatory protein …

Adipokines: biofactors from white adipose tissue. A complex hub among inflammation, metabolism, and immunity

J Conde, M Scotece, R Gómez, V López… - Biofactors, 2011 - Wiley Online Library
Until the identification of leptin, the first adipokine discovered in 1994, adipose tissue was
considered only as an energy storage tissue. However, it is now clear that adipose tissue is …

Role of biomarkers in diagnosis and prognostic evaluation of acute pancreatitis

S Meher, TS Mishra, PK Sasmal, S Rath… - Journal of …, 2015 - Wiley Online Library
Acute pancreatitis is a potentially life threatening disease. The spectrum of severity of the
illness ranges from mild self‐limiting disease to a highly fatal severe necrotizing pancreatitis …

[HTML][HTML] Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis

E Borkham-Kamphorst, E van de Leur… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Lipocalin-2 is expressed under pernicious conditions such as intoxication, infection,
inflammation and other forms of cellular stress. Experimental liver injury induces rapid and …

Circulating cytokines in predicting development of severe acute pancreatitis

A Nieminen, M Maksimow, P Mentula, L Kyhälä… - Critical care, 2014 - Springer
Introduction Severe acute pancreatitis (AP) is associated with high morbidity and mortality.
Early prediction of severe AP is needed to improve patient outcomes. The aim of the present …

Neutrophil gelatinase-associated lipocalin (NGAL) in inflammatory bowel disease: association with pathophysiology of inflammation, established markers, and …

KA Oikonomou, AN Kapsoritakis… - Journal of …, 2012 - Springer
Background Neutrophil gelatinase-associated lipocalin (NGAL) is a multi-potent 25-kDa
protein mainly secreted by neutrophils. In inflammatory bowel disease (IBD), overexpression …

Cytokines chattering in pancreatic ductal adenocarcinoma tumor microenvironment

R Bhatia, N Bhyravbhatla, A Kisling, X Li… - Seminars in cancer …, 2022 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME) consists of
multiple cell types interspersed by dense fibrous stroma. These cells communicate through …

Chronic pancreatitis and the development of pancreatic cancer

HK Kandikattu, SU Venkateshaiah… - Endocrine, Metabolic & …, 2020 - benthamdirect.com
Pancreatitis is a fibro-inflammatory disorder of the pancreas that can occur acutely or
chronically as a result of the activation of digestive enzymes that damage pancreatic cells …

Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis

JL Berard, JG Zarruk, N Arbour, A Prat, VW Yong… - Glia, 2012 - Wiley Online Library
Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model of
multiple sclerosis (MS), an inflammatory, demyelinating disease of the central nervous …

Microcontact surface imprinting of affinity peptide for electrochemical impedimetric detection of neutrophil gelatinase-associated lipocalin

JC Yang, CH Cho, DY Choi, JP Park, J Park - Sensors and Actuators B …, 2022 - Elsevier
In this study, a specific binding peptide (BP1)-imprinted film comprising crosslinked poly
(acrylamide-co-diallyamine-co-N, N′-methylenebisacrylamide) matrix was photochemically …