Ultrasensitive and highly specific lateral flow assays for point-of-care diagnosis

Y Liu, L Zhan, Z Qin, J Sackrison, JC Bischof - ACS nano, 2021 - ACS Publications
Lateral flow assays (LFAs) are paper-based point-of-care (POC) diagnostic tools that are
widely used because of their low cost, ease of use, and rapid format. Unfortunately …

Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N **e… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Review of current COVID-19 diagnostics and opportunities for further development

Y Mardian, H Kosasih, M Karyana, A Neal… - Frontiers in …, 2021 - frontiersin.org
Diagnostic testing plays a critical role in addressing the coronavirus disease 2019 (COVID-
19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV …

CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement

C Li, E Brant, H Budak, B Zhang - Journal of Zhejiang University-SCIENCE …, 2021 - Springer
Since it was first recognized in bacteria and archaea as a mechanism for innate viral
immunity in the early 2010s, clustered regularly interspaced short palindromic repeats …

CRISPR systems for COVID-19 diagnosis

H Rahimi, M Salehiabar, M Barsbay, M Ghaffarlou… - ACS …, 2021 - ACS Publications
The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019,
which has spread rapidly and become a global pandemic. The number of cases of COVID …

Applications and challenges of CRISPR-Cas gene-editing to disease treatment in clinics

W Liu, L Li, J Jiang, M Wu, P Lin - Precision clinical medicine, 2021 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems
(Cas) are efficient tools for targeting specific genes for laboratory research, agricultural …

Integrating CRISPR/Cas within isothermal amplification for point-of-Care Assay of nucleic acid

L Zhang, H Jiang, Z Zhu, J Liu, B Li - Talanta, 2022 - Elsevier
Nucleic acid detection technology is now widely used in scientific research and clinical
testing, such as infectious and genetic diseases screening, molecular diagnosis of tumors …

PAM-free loop-mediated isothermal amplification coupled with CRISPR/Cas12a cleavage (Cas-PfLAMP) for rapid detection of rice pathogens

Z Zhu, R Li, H Zhang, J Wang, Y Lu, D Zhang… - Biosensors and …, 2022 - Elsevier
Pathogenic disease is an important factor affecting rice growth, yield and quality, and the
development and application of rapid diagnostic methods will contribute to the prevention …

Metagenomic discovery of CRISPR-associated transposons

JR Rybarski, K Hu, AM Hill, CO Wilke… - Proceedings of the …, 2021 - National Acad Sciences
CRISPR-associated Tn7 transposons (CASTs) co-opt cas genes for RNA-guided
transposition. CASTs are exceedingly rare in genomic databases; recent surveys have …

Environmental DNA/RNA for pathogen and parasite detection, surveillance, and ecology

D Bass, KW Christison, GD Stentiford, LSJ Cook… - Trends in …, 2023 - cell.com
Detection of pathogens, parasites, and other symbionts in environmental samples via
eDNA/eRNA (collectively eNA) is an increasingly important source of information about their …