Mechanochemical solvent‐free reactions by milling, grinding or other types of mechanical
action have emerged as a viable alternative to solution chemistry. Mechanochemistry offers …

Traditional chemotherapy suffers from severe toxicity and side effects that limit its maximum
application in cancer therapy. To overcome this challenge, an ideal treatment strategy would …

Force-controlled release of small molecules offers great promise for the delivery of drugs
and the release of healing or reporting agents in a medical or materials context,–. In polymer …

Over the decades, the application of mechanical force to influence chemical reactions has
been called by various names: mechanochemistry, tribochemistry, mechanical alloying, to …

Mechanochemistry describes diverse phenomena in which mechanical load affects
chemical reactivity. The fuzziness of this definition means that it includes processes as …

The development of miniaturized electronics has led to the design and construction of
powerful experimental platforms capable of measuring electronic properties to the level of …

Molecular knots and entanglements form randomly and spontaneously in both biological
and synthetic polymer chains. It is known that macroscopic materials, such as ropes, are …

Sacrificial chemical bonds have been used effectively to increase the toughness of
elastomers because such bonds dissociate at forces significantly below the fracture limit of …

Mechanochromic mechanophores permit the design of polymers that indicate mechanical
events through optical signals. Here we report rotaxane-based supramolecular …

Molecular nanotopology—a term we coined recently—is a rapidly develo** field of
research that is emerging out of the confluence of chemical topology with the mechanical …