Management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: AUA guideline part I—initial work-up and medical management

LB Lerner, KT McVary, MJ Barry, BR Bixler… - The Journal of …, 2021 - auajournals.org
Purpose: Benign prostatic hyperplasia (BPH) is a histologic diagnosis describing
proliferation of smooth muscle and epithelial cells within the prostatic transition zone. The …

MRI of benign prostatic hyperplasia: important pre-and posttherapeutic considerations

EA Han, KR Nandalur, MA Morgan, SS Arora… - Radiographics, 2023 - pubs.rsna.org
New minimally invasive techniques that reduce morbidity while improving lower urinary tract
symptoms (LUTS) due to benign prostatic hypertrophy (BPH) have become attractive …

Association of 5α-reductase inhibitors with prostate cancer mortality

L Björnebo, T Nordström, A Discacciati… - JAMA …, 2022 - jamanetwork.com
Importance There is evidence that 5α-reductase inhibitors (5-ARIs), a standard treatment of
benign prostate hyperplasia, are associated with a decrease in the incidence of prostate …

Phosphodiesterase type 5 inhibitor tadalafil reduces prostatic fibrosis via MiR-3126-3p/FGF9 axis in benign prostatic hyperplasia

T Li, Y Zhang, Z Zhou, L Guan, Y Zhang, Z Zhou… - Biology Direct, 2024 - Springer
Myofibroblast buildup and prostatic fibrosis play a crucial role in the development of benign
prostatic hyperplasia (BPH). Treatments specifically targeting myofibroblasts could be a …

Co‐occurrence of lower urinary tract symptoms and frailty among community‐dwelling older men

SR Bauer, R Scherzer, AM Suskind… - Journal of the …, 2020 - Wiley Online Library
BACKGROUND/OBJECTIVES To estimate associations between lower urinary tract
symptoms (LUTS) and phenotypic frailty in older men. DESIGN Cross‐sectional study …

Role of α-and β-adrenergic signaling in phenotypic targeting: significance in benign and malignant urologic disease

M Archer, N Dogra, Z Dovey, T Ganta, HS Jang… - Cell Communication and …, 2021 - Springer
The urinary tract is highly innervated by autonomic nerves which are essential in urinary
tract development, the production of growth factors, and the control of homeostasis. These …

The post-finasteride syndrome: possible etiological mechanisms and symptoms

HHJ Leliefeld, FMJ Debruyne, Y Reisman - International Journal of …, 2023 - nature.com
Finasteride and dutasteride, synthetic 5α-reductase inhibitors (5ARIs) are recommended in
many guidelines for the treatment of benign prostatic hyperplasia/lower urinary tract …

Assessment of frailty and association with progression of benign prostatic hyperplasia symptoms and serious adverse events among men using drug therapy

SR Bauer, LC Walter, KE Ensrud, AM Suskind… - JAMA Network …, 2021 - jamanetwork.com
Importance Benign prostatic hyperplasia (BPH) in older men can cause lower urinary tract
symptoms (LUTS), which are increasingly managed with medications. Frailty may contribute …

Dutasteride for the treatment of androgenetic alopecia: an updated review

Y Ding, C Wang, L Bi, Y Du, C Lu, M Zhao, W Fan - Dermatology, 2024 - karger.com
Background: Androgenetic alopecia (AGA) is a common skin disease characterized by
gradually miniaturized hair follicles, which manifests as progressive hair thinning and …

Frailty and benign prostatic hyperplasia: The thrilling underlying impact

TC Bellos, LI Tzelves, IS Manolitsis… - Archivio Italiano di …, 2022 - pagepressjournals.org
Background: World population is aging. The number of individuals aged over 65 are
expected to be 71 million only in the US. 43% of this population will be men. Benign …