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Role of epigenetics in zebrafish development
The role of epigenetics in development has garnered attention in recent years due to their
ability to modulate the embryonic developmental gene expression in response to the …
ability to modulate the embryonic developmental gene expression in response to the …
Sphingolipids in the heart: from cradle to grave
Cardiovascular diseases are the leading cause of mortality worldwide and this has largely
been driven by the increase in metabolic disease in recent decades. Metabolic disease …
been driven by the increase in metabolic disease in recent decades. Metabolic disease …
[HTML][HTML] Embryonic arsenic exposure triggers long-term behavioral impairment with metabolite alterations in zebrafish
Arsenic trioxide (As2O3) is a ubiquitous heavy metal in the environment. Exposure to this
toxin at low concentrations is unremarkable in develo** organisms. Nevertheless …
toxin at low concentrations is unremarkable in develo** organisms. Nevertheless …
Epigenetic modification factors and microRNAs network associated with differentiation of embryonic stem cells and induced pluripotent stem cells toward …
More research is being conducted on myocardial cell treatments utilizing stem cell lines that
can develop into cardiomyocytes. All of the forms of cardiac illnesses have shown to be quite …
can develop into cardiomyocytes. All of the forms of cardiac illnesses have shown to be quite …
[HTML][HTML] Bioactive lipid signaling in cardiovascular disease, development, and regeneration
Cardiovascular disease (CVD) remains a leading cause of death globally. Understanding
and characterizing the biochemical context of the cardiovascular system in health and …
and characterizing the biochemical context of the cardiovascular system in health and …
MicroRNA-181a promotes follicular granulosa cell apoptosis via sphingosine-1-phosphate receptor 1 expression downregulation
C Zhang, J Shen, S Kong, M Zhang… - Biology of …, 2019 - academic.oup.com
Oxidative stress induces granulosa cell (GC) apoptosis and subsequent follicular atresia.
Since our previous studies indicate that microRNA-181a (miR-181a) expression is …
Since our previous studies indicate that microRNA-181a (miR-181a) expression is …
miR-182-5p is an evolutionarily conserved Tbx5 effector that impacts cardiac development and electrical activity in zebrafish
To dissect the TBX5 regulatory circuit, we focused on microRNAs (miRNAs) that collectively
contribute to make TBX5 a pivotal cardiac regulator. We profiled miRNAs in hearts isolated …
contribute to make TBX5 a pivotal cardiac regulator. We profiled miRNAs in hearts isolated …
Anti-platelet aggregation activities of different grades of Angelica sinensis and their therapeutic mechanisms in rats with blood deficiency: insights from metabolomics …
X Shen, Y Wu, P Chen, Y Bai, Y Liu, Y Jiang… - Frontiers in …, 2024 - frontiersin.org
In traditional Chinese medicine, the radix of Angelica sinensis (Oliv.) Diels (RAS) is mainly
used to replenish and invigorate the blood circulation. This study investigated anti-platelet …
used to replenish and invigorate the blood circulation. This study investigated anti-platelet …
Dysregulated micro-RNAs and long noncoding RNAs in cardiac development and pediatric heart failure
L Toni, F Hailu, CC Sucharov - American Journal of …, 2020 - journals.physiology.org
Noncoding RNAs (ncRNAs) are broadly described as RNA molecules that are not translated
into protein. The investigation of dysregulated ncRNAs in human diseases such as cancer …
into protein. The investigation of dysregulated ncRNAs in human diseases such as cancer …
[HTML][HTML] 基于脂质组学技术发现冠心病的脂质标志物和治疗靶点
杨冠林， 翟琼， 董馨， 布仁， 薛培凤， 赵芳新， 陆景坤 - 药学学报, 2022 - html.rhhz.net
冠心病是全球第一的死亡原因, 其主要特征是冠状动脉粥样硬化使管腔狭窄或闭塞导致心肌缺血
, 缺氧或坏死而引发的心脏病, 冠心病与脂质调节异常, 慢性炎症, 内皮功能障碍等密切相关 …
, 缺氧或坏死而引发的心脏病, 冠心病与脂质调节异常, 慢性炎症, 内皮功能障碍等密切相关 …