Recent developments on other platinum metal complexes as target-specific anticancer therapeutics
TS Prathima, B Choudhury, MG Ahmad… - Coordination Chemistry …, 2023 - Elsevier
Numerous biologically active metal complexes are reported for their unique features and
enhanced functions, particularly towards the inhibition of cancer progression. With the …
enhanced functions, particularly towards the inhibition of cancer progression. With the …
Bioactivity and development of small non-platinum metal-based chemotherapeutics
Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …
development of effective and safe drugs in fighting cancer. Although they still embody a …
Half-Sandwich Iridium(III), Rhodium(III), and Ruthenium(II) Complexes Chelating Hybrid sp2-N/sp3-N Donor Ligands to Achieve Improved Anticancer Selectivity
L Guo, P Li, J Li, Y Gong, X Li, Y Liu, K Yu… - Inorganic …, 2023 - ACS Publications
The biological efficacy of half-sandwich platinum group organometallic complexes of the
formula [(η5-Cpx)/(η6-arene) M (XY) Cl] 0/+(XY= bidentate ligands; Cpx= functionalized …
formula [(η5-Cpx)/(η6-arene) M (XY) Cl] 0/+(XY= bidentate ligands; Cpx= functionalized …
Necroptosis induced by ruthenium (II) complexes as dual catalytic inhibitors of topoisomerase I/II
K **ong, C Qian, Y Yuan, L Wei, X Liao… - Angewandte Chemie …, 2020 - Wiley Online Library
Inducing necroptosis in cancer cells is an effective approach to circumvent drug‐resistance.
Metal‐based triggers have, however, rarely been reported. Ruthenium (II) complexes …
Metal‐based triggers have, however, rarely been reported. Ruthenium (II) complexes …
Increasing anticancer activity with phosphine ligation in zwitterionic half-sandwich iridium (III), rhodium (III), and ruthenium (II) complexes
X Hu, L Guo, M Liu, Q Zhang, Y Gong, M Sun… - Inorganic …, 2022 - ACS Publications
The synthesis and biological assessment of neutral or cationic platinum group metal-based
anticancer complexes have been extremely studied, whereas there are few reports on the …
anticancer complexes have been extremely studied, whereas there are few reports on the …
Multifaceted chemical behaviour of metallocene (M= Fe, Os) quinone methides. Their contribution to biology
Organometallic quinone methides (OM-QMs) have unique chemical and biological
properties compared to their purely organic counterparts, but their originality has not …
properties compared to their purely organic counterparts, but their originality has not …
Recent advances in biological activities of rhodium complexes: Their applications in drug discovery research
Unique structure, characteristic reactivity, and facile synthesis of metal complexes have
made them efficient ligands in drug development research. Among them, rhodium …
made them efficient ligands in drug development research. Among them, rhodium …
Metal complexes or chelators with ROS regulation capacity: Promising candidates for cancer treatment
X Li, Y Wang, M Li, H Wang, X Dong - Molecules, 2021 - mdpi.com
Reactive oxygen species (ROS) are rapidly eliminated and reproduced in organisms, and
they always play important roles in various biological functions and abnormal pathological …
they always play important roles in various biological functions and abnormal pathological …
Mitochondria-targeted iridium-based photosensitizers enhancing photodynamic therapy effect by disturbing cellular redox balance
M Zhong, J He, B Zhang, Q Liu, J Fang - Free Radical Biology and …, 2023 - Elsevier
Photodynamic therapy (PDT) is a non-invasive, light-activated treatment approach that has
been broadly employed in cancer. Cyclometallic iridium (Ш) complexes are candidates for …
been broadly employed in cancer. Cyclometallic iridium (Ш) complexes are candidates for …
Probing the Paradigm of Promiscuity for N‐Heterocyclic Carbene Complexes and their Protein Adduct Formation
Metal complexes can be considered a “paradigm of promiscuity” when it comes to their
interactions with proteins. They often form adducts with a variety of donor atoms in an …
interactions with proteins. They often form adducts with a variety of donor atoms in an …