Intervention at the earliest illness stage, in ultra or clinical high-risk individuals, or indicated
prevention, currently represents the most promising strategy to ameliorate, delay or prevent …

BackgroundCurrently there is no first-line treatment recommended for the negative
symptoms of schizophrenia. Psychosocial and behavioural interventions are widely used to …

Abstract Background and Hypothesis Individuals at clinical high risk for psychosis (CHR-p)
are less fit than nonclinical peers and show hippocampal abnormalities that relate to clinical …

Longitudinal prospective cohorts have suggested that physical activity (PA) may be a
protective factor against psychosis and schizophrenia. However, no meta-analysis has been …

Introduction Converging evidence suggests that hippocampal subregions subserve different
functions, and are differentially affected by psychosis illness progression. Despite this fact …

Background: The clinical high risk for psychosis (CHR-P) construct represents an
opportunity for prevention and early intervention in young adults, but the relationship …

We aimed to perform a systematic review and meta-analysis of appetite regulating
hormones in patients with first-episode psychosis (FEP). Meta-analyses were conducted …

Adolescence is among the most vulnerable period for the emergence of serious mental
illnesses. Addressing this vulnerability has generated interest in identifying markers of risk …

Recently, genuine motor abnormalities have been recognized as prodromal and predictive
signs of psychosis onset and progression. Therefore, physical exercise could represent a …

Abstract Background and Hypothesis Aerobic exercise interventions in people with
schizophrenia have been demonstrated to improve clinical outcomes, but findings regarding …