Integrated MRI-guided radiotherapy—opportunities and challenges

PJ Keall, C Brighi, C Glide-Hurst, G Liney… - Nature Reviews …, 2022 - nature.com
MRI can help to categorize tissues as malignant or non-malignant both anatomically and
functionally, with a high level of spatial and temporal resolution. This non-invasive imaging …

MR-guidance in clinical reality: current treatment challenges and future perspectives

S Corradini, F Alongi, N Andratschke, C Belka… - Radiation …, 2019 - Springer
Abstract Magnetic Resonance-guided radiotherapy (MRgRT) marks the beginning of a new
era. MR is a versatile and suitable imaging modality for radiotherapy, as it enables direct …

Association of ablative radiation therapy with survival among patients with inoperable pancreatic cancer

M Reyngold, EM O'Reilly, AM Varghese… - JAMA …, 2021 - jamanetwork.com
Importance Surgical resection has been considered the only curative option for patients with
pancreatic cancer. Nonoperative local treatment options that can provide a similar benefit …

Magnetic resonance linear accelerator technology and adaptive radiation therapy: An overview for clinicians

WA Hall, E Paulson, XA Li, B Erickson… - CA: a cancer journal …, 2022 - Wiley Online Library
Radiation therapy (RT) continues to play an important role in the treatment of cancer.
Adaptive RT (ART) is a novel method through which RT treatments are evolving. With the …

[HTML][HTML] Targeted delivery of drugs and genes using polymer nanocarriers for cancer therapy

W **a, Z Tao, B Zhu, W Zhang, C Liu, S Chen… - International journal of …, 2021 - mdpi.com
Cancer is one of the primary causes of worldwide human deaths. Most cancer patients
receive chemotherapy and radiotherapy, but these treatments are usually only partially …

FLASH: New intersection of physics, chemistry, biology, and cancer medicine

MC Vozenin, BW Loo Jr, S Tantawi, PG Maxim… - Reviews of Modern …, 2024 - APS
Ultrahigh dose rate, FLASH radiotherapy has emerged as one of the most promising
innovations over the past decade in the field of radiation oncology, with the potential to …

[HTML][HTML] Ablative 5-fraction stereotactic magnetic resonance–guided radiation therapy with on-table adaptive replanning and elective nodal irradiation for inoperable …

MD Chuong, J Bryant, KE Mittauer, M Hall… - Practical radiation …, 2021 - Elsevier
Purpose Radiation therapy dose escalation using stereotactic body radiation therapy may
significantly improve both local control (LC) and overall survival (OS) for patients with …

[HTML][HTML] A multi-institutional phase 2 trial of ablative 5-fraction stereotactic magnetic resonance-guided on-table adaptive radiation therapy for borderline resectable …

PJ Parikh, P Lee, DA Low, J Kim, KE Mittauer… - International Journal of …, 2023 - Elsevier
Purpose Magnetic resonance (MR) image guidance may facilitate safe ultrahypofractionated
radiation dose escalation for inoperable pancreatic ductal adenocarcinoma. We conducted …

MRI-LINAC: A transformative technology in radiation oncology

J Ng, F Gregucci, RT Pennell, H Nagar… - Frontiers in …, 2023 - frontiersin.org
Advances in radiotherapy technologies have enabled more precise target guidance,
improved treatment verification, and greater control and versatility in radiation delivery …

[HTML][HTML] Stereotactic MR-guided on-table adaptive radiation therapy (SMART) for borderline resectable and locally advanced pancreatic cancer: A multi-center, open …

MD Chuong, P Lee, DA Low, J Kim, KE Mittauer… - Radiotherapy and …, 2024 - Elsevier
Background and purpose Radiation dose escalation may improve local control (LC) and
overall survival (OS) in select pancreatic ductal adenocarcinoma (PDAC) patients. We …