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Pharmacological and non-pharmacological approaches for the management of neuropathic pain in multiple sclerosis
Multiple sclerosis is a chronic inflammatory disease that affects the central nervous system
and can cause various types of pain including ongoing extremity pain, Lhermitte's …
and can cause various types of pain including ongoing extremity pain, Lhermitte's …
The disruptive relationship among circadian rhythms, pain, and opioids
Pain behavior and the systems that mediate opioid analgesia and opioid reward processing
display circadian rhythms. Moreover, the pain system and opioid processing systems …
display circadian rhythms. Moreover, the pain system and opioid processing systems …
Circadian pain patterns in human pain conditions–A systematic review
Background Chronobiology is the science of how physiological processes in the body follow
a pattern of time. Pain has been shown to follow a circadian rhythm, with different types of …
a pattern of time. Pain has been shown to follow a circadian rhythm, with different types of …
DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa
Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that
affects hair follicles in areas with apocrine sweat glands, such as the underarms, groin, and …
affects hair follicles in areas with apocrine sweat glands, such as the underarms, groin, and …
The challenge of ecological validity in temporomandibular disorders research
JC Nickel, YM Gonzalez, LM Gallo… - Journal of Oral …, 2024 - Wiley Online Library
Objective To review the ecological validity of outcomes from current research involving
temporomandibular disorders (TMDs), with an emphasis on chronic myofascial pain and the …
temporomandibular disorders (TMDs), with an emphasis on chronic myofascial pain and the …
Circadian rhythm and pain: A review of current research and future implications
Abstract Purpose of Review The goal is to examine the link between circadian rhythms and
pain, which may shed further light on improving pain management strategies and preventing …
pain, which may shed further light on improving pain management strategies and preventing …
Sleep phase and pre-sleep arousal predicted co-developmental trajectories of pain and insomnia within adolescence
The onset of both chronic pain and insomnia is high during adolescence. Although a
bidirectional relationship between pain and insomnia has support, how pain and sleep co …
bidirectional relationship between pain and insomnia has support, how pain and sleep co …
Suppression of neuropathic pain in the circadian clock–deficient Per2m/m mice involves up-regulation of endocannabinoid system
W Yamakawa, S Yasukochi, Y Tsurudome… - PNAS …, 2024 - academic.oup.com
Neuropathic pain often results from injuries and diseases that affect the somatosensory
system. Disruption of the circadian clock has been implicated in the exacerbation of the …
system. Disruption of the circadian clock has been implicated in the exacerbation of the …
Persistent idiopathic dentoalveolar pain: Is it a central pain disorder?
Defined by the International Classification of Orofacial Pain (ICOP) 6.3, persistent idiopathic
dentoalveolar pain (PIDP) is a persistent unilateral intraoral dentoalveolar pain, rarely …
dentoalveolar pain (PIDP) is a persistent unilateral intraoral dentoalveolar pain, rarely …
BioClocks UK: driving robust cycles of discovery to impact
H Rees, NM Rzechorzek… - Philosophical …, 2025 - royalsocietypublishing.org
Chronobiology is a multidisciplinary field that extends across the tree of life, transcends all
scales of biological organization, and has huge translational potential. For the UK to harness …
scales of biological organization, and has huge translational potential. For the UK to harness …