The rodent forced swim test measures stress-co** strategy, not depression-like behavior

KG Commons, AB Cholanians, JA Babb… - ACS chemical …, 2017 - ACS Publications
The forced swim test (FST) measures co** strategy to an acute inescapable stress and
thus provides unique insight into the neural limb of the stress response. Stress, particularly …

Mechanisms of action and persistent neuroplasticity by drugs of abuse

ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - Elsevier
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress

J Sun, F Wang, G Hong, M Pang, H Xu, H Li, F Tian… - Neuroscience …, 2016 - Elsevier
Sodium butyrate (NaB) has exhibited neuroprotective activity. This study aimed to explore
that NaB exerts beneficial effects on chronic unpredictable mild stress (CUMS)-induced …

Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar longlasting deficits in object recognition and reduced social …

M O'Shea, IS McGregor… - Journal of …, 2006 - journals.sagepub.com
There is mounting evidence that chronic cannabis use might result in lasting
neurobehavioural changes, although it remains unclear whether vulnerability diminishes …

MDMA and memory, addiction, and depression: dose-effect analysis

MM Pantoni, JL Kim, KR Van Alstyne… - …, 2022 - Springer
Abstract Rationale±3, 4-Methylenedioxymethamphetamine (MDMA) is a recreational drug
that shows substantial promise as a psychotherapeutic agent. Still, there is some concern …

From ultrasocial to antisocial: a role for oxytocin in the acute reinforcing effects and long‐term adverse consequences of drug use?

IS McGregor, PD Callaghan… - British journal of …, 2008 - Wiley Online Library
Addictive drugs can profoundly affect social behaviour both acutely and in the long‐term.
Effects range from the artificial sociability imbued by various intoxicating agents to the …

Neurotoxicity of methylenedioxyamphetamines (MDMA; ecstasy) in humans: how strong is the evidence for persistent brain damage?

E Gouzoulis‐Mayfrank, J Daumann - Addiction, 2006 - Wiley Online Library
Background The popular dance drug ecstasy (3, 4‐methylenedioxymethamphetamine:
MDMA and some analogues) causes selective and persistent neurotoxic damage of central …

Long-term cognitive and neurochemical effects of “bath salt” designer drugs methylone and mephedrone

B den Hollander, S Rozov, AM Linden… - Pharmacology …, 2013 - Elsevier
INTRODUCTION/AIMS: The use of cathinone-derivative designer drugs methylone and
mephedrone has increased rapidly in recent years. Our aim was to investigate the possible …

MDMA in humans: factors which affect the neuropsychobiological profiles of recreational ecstasy users, the integrative role of bioenergetic stress

AC Parrott - Journal of Psychopharmacology, 2006 - journals.sagepub.com
Many recreational ecstasy/MDMA users display neuropsychobiological de. cits, whereas
others remain problem free. This review will investigate some of the drug and non-drug …

Withdrawal from chronic, intermittent access to a highly palatable food induces depressive-like behavior in compulsive eating rats

A Iemolo, M Valenza, L Tozier, CM Knapp… - Behavioural …, 2012 - journals.lww.com
The increased availability of highly palatable foods is a major contributing factor toward the
development of compulsive eating in obesity and eating disorders. It has been proposed that …