Unveiling microbial diversity: harnessing long-read sequencing technology

DP Agustinho, Y Fu, VK Menon, GA Metcalf… - Nature …, 2024 - nature.com
Long-read sequencing has recently transformed metagenomics, enhancing strain-level
pathogen characterization, enabling accurate and complete metagenome-assembled …

Modern microbiology: Embracing complexity through integration across scales

AM Eren, JF Banfield - Cell, 2024 - cell.com
Microbes were the only form of life on Earth for most of its history, and they still account for
the vast majority of life's diversity. They convert rocks to soil, produce much of the oxygen we …

Oxford Nanopore R10. 4 long-read sequencing enables the generation of near-finished bacterial genomes from pure cultures and metagenomes without short-read or …

M Sereika, RH Kirkegaard, SM Karst, TY Michaelsen… - Nature …, 2022 - nature.com
Abstract Long-read Oxford Nanopore sequencing has democratized microbial genome
sequencing and enables the recovery of highly contiguous microbial genomes from isolates …

High-quality metagenome assembly from long accurate reads with metaMDBG

G Benoit, S Raguideau, R James, AM Phillippy… - Nature …, 2024 - nature.com
We introduce metaMDBG, a metagenomics assembler for PacBio HiFi reads. MetaMDBG
combines a de Bruijn graph assembly in a minimizer space with an iterative assembly over …

Methyl-reducing methanogenesis by a thermophilic culture of Korarchaeia

V Krukenberg, AJ Kohtz, ZJ Jay, R Hatzenpichler - Nature, 2024 - nature.com
Methanogenesis mediated by archaea is the main source of methane, a strong greenhouse
gas, and thus is critical for understanding Earth's climate dynamics. Recently, genes …

Long-read metagenomics paves the way toward a complete microbial tree of life

M Albertsen - Nature Methods, 2023 - nature.com
Long-read metagenomics paves the way toward a complete microbial tree of life | Nature
Methods Skip to main content Thank you for visiting nature.com. You are using a browser …

A high-quality genome compendium of the human gut microbiome of Inner Mongolians

H **, K Quan, Q He, LY Kwok, T Ma, Y Li, F Zhao… - Nature …, 2023 - nature.com
Metagenome-based resources have revealed the diversity and function of the human gut
microbiome, but further understanding is limited by insufficient genome quality and a lack of …

Phylogenomic analysis of Wolbachia genomes from the Darwin Tree of Life biodiversity genomics project

E Vancaester, M Blaxter - PLoS Biology, 2023 - journals.plos.org
The Darwin Tree of Life (DToL) project aims to sequence all described terrestrial and
aquatic eukaryotic species found in Britain and Ireland. Reference genome sequences are …

HiFi metagenomic sequencing enables assembly of accurate and complete genomes from human gut microbiota

CY Kim, J Ma, I Lee - Nature communications, 2022 - nature.com
Advances in metagenomic assembly have led to the discovery of genomes belonging to
uncultured microorganisms. Metagenome-assembled genomes (MAGs) often suffer from …

SemiBin2: self-supervised contrastive learning leads to better MAGs for short-and long-read sequencing

S Pan, XM Zhao, LP Coelho - Bioinformatics, 2023 - academic.oup.com
Motivation Metagenomic binning methods to reconstruct metagenome-assembled genomes
(MAGs) from environmental samples have been widely used in large-scale metagenomic …