Parallel evolution of nacre building gene sets in molluscs

DJ Jackson, C McDougall, B Woodcroft… - Molecular biology …, 2010 - academic.oup.com
The capacity to biomineralize is closely linked to the rapid expansion of animal life during
the early Cambrian, with many skeletonized phyla first appearing in the fossil record at this …

Sponges: A reservoir of genes implicated in human cancer

H Ćetković, M Halasz, M Herak Bosnar - Marine drugs, 2018 - mdpi.com
Recently, it was shown that the majority of genes linked to human diseases, such as cancer
genes, evolved in two major evolutionary transitions—the emergence of unicellular …

Demosponge EST sequencing reveals a complex genetic toolkit of the simplest metazoans

M Harcet, M Roller, H Ćetković, D Perina… - Molecular biology …, 2010 - academic.oup.com
Sponges (Porifera) are among the simplest living and the earliest branching metazoans.
They hold a pivotal role for studying genome evolution of the entire metazoan branch, both …

[HTML][HTML] A survey of metastasis suppressors in Metazoa

H Ćetković, M Harcet, M Roller, MH Bosnar - Laboratory investigation, 2018 - Elsevier
Metastasis suppressors are genes/proteins involved in regulation of one or more steps of the
metastatic cascade while having little or no effect on tumor growth. The list of putative …

Transfection of sponge cells and intracellular localization of cancer-related MYC, RRAS2, and DRG1 proteins

K Dominko, A Talajić, M Radić, NŠ Vidaček… - Marine drugs, 2023 - mdpi.com
The determination of the protein's intracellular localization is essential for understanding its
biological function. Protein localization studies are mainly performed on primary and …

Structure and function of cancer-related developmentally regulated GTP-binding protein 1 (DRG1) is conserved between sponges and humans

S Beljan, K Dominko, A Talajić, A Hloušek-Kasun… - Scientific reports, 2022 - nature.com
Cancer is a disease caused by errors within the multicellular system and it represents a
major health issue in multicellular organisms. Although cancer research has advanced …

Sponge non-metastatic Group I Nme gene/protein-structure and function is conserved from sponges to humans

D Perina, MH Bosnar, R Bago, A Mikoč, M Harcet… - BMC evolutionary …, 2011 - Springer
Background Nucleoside diphosphate kinases NDPK are evolutionarily conserved enzymes
present in Bacteria, Archaea and Eukarya, with human Nme1 the most studied …

Genome-wide identification, evolution and expression of the complete set of cytoplasmic ribosomal protein genes in Nile Tilapia

G Kuang, W Tao, S Zheng, X Wang… - International Journal of …, 2020 - mdpi.com
Ribosomal proteins (RPs) are indispensable in ribosome biogenesis and protein synthesis,
and play a crucial role in diverse developmental processes. In the present study, we carried …

Characterization of Nme6-like gene/protein from marine sponge Suberites domuncula

D Perina, MH Bosnar, A Mikoč, WEG Müller… - Naunyn-Schmiedeberg's …, 2011 - Springer
Nucleoside diphosphate kinases (NDPKs) are evolutionarily conserved enzymes involved in
many biological processes such as metastasis, proliferation, development, differentiation …

[HTML][HTML] Over-represented localized sequence motifs in ribosomal protein gene promoters of basal metazoans

D Perina, M Korolija, M Roller, M Harcet, B Jeličić… - Genomics, 2011 - Elsevier
Equimolecular presence of ribosomal proteins (RPs) in the cell is needed for ribosome
assembly and is achieved by synchronized expression of ribosomal protein genes (RPGs) …