Abstract Purpose of Review Immunoglobulin A (IgA) mediates immune exclusion of antigens
in the gut. Notably, IgA plays also a role in the prevention of IgE-mediated allergies and …

An increasing number of human diseases, including allergies, infections, inflammation, and
cancer, involve roles for basophils. Traditionally viewed as the rarest leukocytes that are …

Pectins are dietary fibers that are attributed with several beneficial immunomodulatory
effects. Depending on the degree of esterification (DE), pectins can be classified as high …

Background We investigated the biological function of the mould allergen Alt a 1 as a carrier
of micronutrients, such as the vitamin A metabolite retinoic acid (RA) and the influence of RA …

Autoimmunity is the break of tolerance to self‐antigens that leads to organ‐specific or
systemic diseases often characterized by the presence of pathogenic autoreactive …

Food allergy, a group of adverse immune responses to normally innocuous food protein
antigens, is an increasingly prevalent public health issue. The most common form is IgE …

The prevalence of asthma, rhinitis, and food allergies has increased dramatically over the
last few decades. This increase originally started in western countries, but is now also …

Despite the near ubiquitous presence of Ig‐based antibodies in vertebrates, IgE is unique to
mammals. How and why it emerged remains mysterious. IgE expression is greatly …

Background IgA is the most abundant immunoglobulin at the mucosal surface and although
its role in regulating mucosal immunity is not fully understood, its presence is associated …

Simple Summary It has long been known that antibodies of a certain class, called IgE, are
the main cause of allergic reactions to food. Other antibody types such as IgA and IgG can …