[HTML][HTML] Machine Perfusion as a Strategy to Decrease Ischemia-Reperfusion Injury and Lower Cancer Recurrence Following Liver Transplantation

KB Garcia, A Hussein, S Satish, CJ Wehrle… - Cancers, 2024‏ - mdpi.com
Liver transplantation (LT) is a key treatment for primary and secondary liver cancers,
reducing tumor burden with concurrent improvement of liver function. While significant …

[HTML][HTML] Challenges in Liver Transplantation for Hepatocellular Carcinoma: A Review of Current Controversies

E Mauro, M Sanduzzi-Zamparelli, G Jutras, R Garcia… - Cancers, 2024‏ - mdpi.com
Simple Summary Liver transplantation (LT) is one of the primary treatments for
hepatocellular carcinoma (HCC) and significantly improves patient survival. However, the …

[HTML][HTML] PET-Assessed Metabolic Tumor Volume Across the Spectrum of Solid-Organ Malignancies: A Review of the Literature

A Agarwal, CJ Wehrle, S Satish, P Mahajan, S Kamath… - Biomedicines, 2025‏ - mdpi.com
Solid-organ malignancies represent a significant disease burden and remain one of the
leading causes of death globally. In the past few decades, the rapid evolution of imaging …

The assessment of impaired liver function and prognosis in hepatocellular carcinoma

R Pantea, J Bednarsch, S Schmitz… - Expert Review of …, 2024‏ - Taylor & Francis
Introduction The impairment of liver function strongly limits the therapeutic options for
hepatocellular carcinoma (HCC), and the assessment of liver function is key to finding the …

[HTML][HTML] Immune Checkpoint Inhibitors in the Pre-Transplant Hepatocellular Carcinoma Setting: A Glimpse Beyond the Liver

L Marzi, A Mega, C Turri, S Gitto… - … Journal of Molecular …, 2024‏ - pmc.ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the third
leading cause of cancer-related death worldwide. Liver transplantation (LT) is the best …

Assessing the Causal Effect of Circulating Protein‐To‐Protein Ratio on the Risk of Morbidity of Hepatocellular Carcinoma

Q Yue, X Li, X Wan, X Lin, Y Li, M Zhang… - Cancer Medicine, 2025‏ - Wiley Online Library
Objective Several observational studies have identified an association between plasma
proteins and hepatocellular carcinoma (HCC). This study aimed to explore the potential …

[HTML][HTML] Advanced approaches to loco-regional and surgical management for hepatocellular carcinoma

CJ Wehrle, W Archie, D Vrochides… - Journal of …, 2024‏ - pmc.ncbi.nlm.nih.gov
Advanced approaches to loco-regional and surgical management for hepatocellular carcinoma
- PMC Skip to main content Here's how you know Official websites use .gov A .gov website …

[HTML][HTML] Immunotherapy in Liver Transplantation for Hepatocellular Carcinoma: A Comprehensive Review

M Akabane, Y Imaoka, J Kawashima, A Schenk… - Journal of Liver …, 2024‏ - Elsevier
Immunotherapy has emerged as a transformative approach in the treatment of
hepatocellular carcinoma (HCC), particularly through the use of immune checkpoint …

Reply: Oncologic optimization of patients with colorectal liver metastatic disease–An ongoing saga

C Wehrle, K Hashimoto, F Aucejo - Liver Transplantation, 2025‏ - journals.lww.com
Regarding deceased versus living donors, they correctly note that many patients with
colorectal cancer liver metastasis have low MELD scores and would be low on the organ …

Liver Transplant for Nonhepatocellular Carcinoma Tumors: A Review of Expanding Indications in Nontraditional Transplant Oncology

CJ Wehrle, S Fares, K Shanmugarajah… - Digestive Disease …, 2024‏ - thieme-connect.com
Liver transplantation (LT) is a life-saving procedure most well-known in the curative
treatment of cirrhosis or end-stage liver disease. The approach is also well established for …