Microglia has the potential to shape the neuroimmune defense with vast array of functional
attributes. The cells prime infiltrated lymphocytes to retain their effector functions, play crucial …

Recent increase in the occurrence of intracranial malignancies and poor performance of
therapeutic measures have established the disease as an important concern of medical …

The brain represents a significant barrier for protective immune responses in both infectious
disease and cancer. We have recently demonstrated that immunotherapy with anti-CD40 …

The specific apoptotic role of T11TS has been well established in glioma animal models.
T11TS specifically induces the glioma cells to die an apoptotic death via immune cross-talk …

Abstract Statement of the Problem: The sheep erythrocyte membrane glycoprotein
T11TS/SLFA-3 can form a ligand-receptor complex with CD2 present on immunocyte and …

Free radicals and allied molecules are the potential threats for the cellular components
when they are produced in excess amount and cause different pathophysiological disorders …

Brain tumors of glial origin ie glioma are most difficult neoplasm to treat with modern
therapeutic interventions viz. surgery, radio-and chemotherapies. Therefore, a continuous …

T11TS/SLFA-3, the glycoprotein isolated from sheep erythrocyte membrane, acts as an
antineoplastic agent causing apoptotic elimination of glioma cells through cell mediated …

Aim: Microglia, the innate defence cells in central nervous system (CNS), alters their shapes
and function with age. We observed and identified these morphological changes and …

The significant insights into the immunobiology of central nervous system (CNS) and brain
tumor have opened up the feasibility of applying'Immunotherapy'as an alternative to the poor …