How a fungus shapes biotechnology: 100 years of Aspergillus niger research

TC Cairns, C Nai, V Meyer - Fungal biology and biotechnology, 2018 - Springer
In 1917, a food chemist named James Currie made a promising discovery: any strain of the
filamentous mould Aspergillus niger would produce high concentrations of citric acid when …

Aspergillus fumigatus and Aspergillosis

JP Latgé - Clinical microbiology reviews, 1999 - journals.asm.org
Aspergillus fumigatus is one of the most ubiquitous of the airborne saprophytic fungi.
Humans and animals constantly inhale numerous conidia of this fungus. The conidia are …

Identification and characterization of MPG1, a gene involved in pathogenicity from the rice blast fungus Magnaporthe grisea.

NJ Talbot, DJ Ebbole, JE Hamer - The Plant Cell, 1993 - academic.oup.com
Differential cDNA cloning was used to identify genes expressed during infectious growth of
the fungal pathogen Magnaporthe grisea in its host, the rice plant. We characterized one of …

Agrobacterium tumefaciens-mediated transformation of filamentous fungi

MJA De Groot, P Bundock, PJJ Hooykaas… - Nature …, 1998 - nature.com
Agrobacterium tumefaciens transfers part of its Ti plasmid, the T-DNA, to plant cells during
tumorigenesis. It is routinely used for the genetic modification of a wide range of plant …

Infection patterns in barley and wheat spikes inoculated with wild-type and trichodiene synthase gene disrupted Fusarium graminearum

C Jansen, D Von Wettstein, W Schäfer… - Proceedings of the …, 2005 - pnas.org
Fusarium head blight epidemics of wheat and barley cause heavy economic losses to
farmers due to yield decreases and production of mycotoxin that renders the grain useless …

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus

MG Fraczek, M Bromley, A Buied… - Journal of …, 2013 - academic.oup.com
Objectives Recent increases in triazole resistance in Aspergillus fumigatus have been
attributed primarily to target site (cyp51A) mutations. A recent survey of resistant isolates in …

Cloning and molecular characterization of the glyceraldehyde-3-phosphate dehydrogenase-encoding gene and cDNA from the plant pathogenic fungus Glomerella …

MD Templeton, EHA Rikkerink, SL Solon… - Gene, 1992 - Elsevier
The glyceraldehyde-3-phosphate dehydrogenase gene (gpdA) has been identified from a
genomic DNA library prepared from the plant pathogenic fungus Glomerella cingulata …

Construction of an improved mycoinsecticide overexpressing a toxic protease.

RJ St Leger, L Joshi, MJ Bidochka… - Proceedings of the …, 1996 - pnas.org
Mycoinsecticides are being used for the control of many insect pests as an environmentally
acceptable alternative to chemical insecticides. A key aim of much recent work has been to …

Siderophore Biosynthesis But Not Reductive Iron Assimilation Is Essential for Aspergillus fumigatus Virulence

M Schrettl, E Bignell, C Kragl, C Joechl… - The Journal of …, 2004 - rupress.org
The ability to acquire iron in vivo is essential for most microbial pathogens. Here we show
that Aspergillus fumigatus does not have specific mechanisms for the utilization of host iron …

Fungal biofilm architecture produces hypoxic microenvironments that drive antifungal resistance

CH Kowalski, KA Morelli, D Schultz, CD Nadell… - Proceedings of the …, 2020 - pnas.org
Human fungal infections may fail to respond to contemporary antifungal therapies in vivo
despite in vitro fungal isolate drug susceptibility. Such a discrepancy between in vitro …