Bones provide mechanical and protective function, while also serving as housing for marrow
and a site for regulation of calcium ion homeostasis. The properties of bones do not remain …

Bone fragility is a major health concern, as the increased risk of bone fractures has
devastating outcomes in terms of mortality, decreased autonomy, and healthcare costs …

Mechanical load of the skeleton system is essential for the development, growth, and
maintenance of bone. However, the molecular mechanism by which mechanical stimuli are …

Osteoporosis, a classical age-related disease and known to be more common in women
than in men, has been reported increasingly often in men during the past few years …

Mobility patterns affect the loads placed on the lower limbs during locomotion and may
influence variation in lower limb diaphyseal robusticity and shape. This relationship …

Quantitative assessment of the strength and toughness of bone has become an integral part
of many biological and bioengineering studies on the structural properties of bone and their …

Small leucine rich proteoglycans (SLRPs), including Biglycan, have key roles in many organ
and tissue systems. The goal of this article is to review the function of Biglycan and other …

Background: Although weight loss and exercise ameliorates frailty and improves cardiac risk
factors in obese older adults, the long-term effect of lifestyle intervention on bone …

Bone is not only a dynamic living tissue, but also a composite material with a complex
hierarchical structure, responsible for bone's remarkable functionality. However, advanced …

Abstract Purpose of Review In this review we aim to summarize the latest findings on the
network of molecules produced by muscle and bone under physiological and pathological …