Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Conquering the hypoxia limitation for photodynamic therapy

Y Wan, LH Fu, C Li, J Lin, P Huang - Advanced Materials, 2021 - Wiley Online Library
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …

Supramolecular photosensitizer enables oxygen-independent generation of hydroxyl radicals for photodynamic therapy

KX Teng, LY Niu, QZ Yang - Journal of the American Chemical …, 2023 - ACS Publications
The highly oxygen-dependent nature of photodynamic therapy (PDT) limits its therapeutic
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …

Biological utility of fluorinated compounds: from materials design to molecular imaging, therapeutics and environmental remediation

C Zhang, K Yan, C Fu, H Peng, CJ Hawker… - Chemical …, 2021 - ACS Publications
The applications of fluorinated molecules in bioengineering and nanotechnology are
expanding rapidly with the controlled introduction of fluorine being broadly studied due to …

Nanomedicine‐Enabled Sonomechanical, Sonopiezoelectric, Sonodynamic, and Sonothermal Therapy

X Song, Q Zhang, M Chang, L Ding… - Advanced …, 2023 - Wiley Online Library
Nanomedicine‐enabled/augmented ultrasound (US) medicine is a unique area of
interdisciplinary research that focuses on designing and engineering functional …

Clinical development and potential of photothermal and photodynamic therapies for cancer

X Li, JF Lovell, J Yoon, X Chen - Nature reviews Clinical oncology, 2020 - nature.com
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available …

The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Fluoropolymers in biomedical applications: state-of-the-art and future perspectives

J Lv, Y Cheng - Chemical Society Reviews, 2021 - pubs.rsc.org
Fluoropolymers have unique physicochemical properties such as hydrophobicity and
lipophobicity, good chemical stability and bio-inertness, low surface energy and phase …

An NIR‐II Photothermally Triggered “Oxygen Bomb” for Hypoxic Tumor Programmed Cascade Therapy

S Zhang, Z Li, Q Wang, Q Liu, W Yuan… - Advanced …, 2022 - Wiley Online Library
Hypoxia, as a characteristic feature of solid tumors, has a close relationship with tumor
resistance to photodynamic therapy (PDT) and chemotherapy. Perfluorocarbon (PFC) is …

Reactive oxygen species‐regulating strategies based on nanomaterials for disease treatment

C Zhang, X Wang, J Du, Z Gu, Y Zhao - Advanced Science, 2021 - Wiley Online Library
Reactive oxygen species (ROS) play an essential role in physiological and pathological
processes. Studies on the regulation of ROS for disease treatments have caused wide …