Since its discovery in 2007, the encephalitis associated with antibodies against the N-methyl-
D-aspartate receptor (NMDAR) has entered the mainstream of neurology and other …

Schizophrenia is a serious mental disorder that affects up to 1% of the population worldwide.
As of yet, neurochemical mechanisms underlying schizophrenia remain unknown. To date …

We recently described a severe, potentially lethal, but treatment-responsive encephalitis that
associates with autoantibodies to the NMDA receptor (NMDAR) and results in behavioral …

Cognitive deficits in schizophrenia are among the core symptoms of the disease, correlate
with functional outcome, and are not well treated with current antipsychotic therapies. In …

The objective of this review is to identify a target or biomarker of altered neurochemical
sensitivity that is common to the many animal models of human psychoses associated with …

Prenatal exposure to infections represents a risk factor for the emergence of
neuropsychiatric disorders in later life, including schizophrenia and autism. However, it …

Maternal infection during pregnancy is a notable risk factor for the offspring to develop
severe neuropsychiatric disorders, including schizophrenia. One prevalent hypothesis …

Anti-NMDAR encephalitis is a severe but treatable disorder that frequently affects children
and adolescents and is likely under-recognized. The syndrome is highly predictable …

Objective To review the evidence that agents which preferentially affect serotonin (5-HT)
attenuate the ability of N-methyl-D-aspartate (NMDA) receptor non-competitive antagonists …

Brain dopamine is critically involved in movement control, and its deficiency is the primary
cause of motor symptoms in Parkinson disease. Here we report development of an animal …