Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K **a, Q **a, Y Liu, X Zhang - Chemical Reviews, 2024 - ACS Publications
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

Coumarin-based small-molecule fluorescent chemosensors

D Cao, Z Liu, P Verwilst, S Koo, P Jangjili… - Chemical …, 2019 - ACS Publications
Coumarins are a very large family of compounds containing the unique 2 H-chromen-2-one
motif, as it is known according to IUPAC nomenclature. Coumarin derivatives are widely …

Mitochondria-Targeting Multifunctional Fluorescent Probe toward Polarity, Viscosity, and ONOO and Cell Imaging

Y Huang, M Li, Q Zan, R Wang, S Shuang… - Analytical …, 2023 - ACS Publications
Abnormal changes occurring in the mitochondrial microenvironment are important markers
indicating mitochondrial and cell dysfunction. Herein, we designed and synthesized a …

Upconversion NIR-II fluorophores for mitochondria-targeted cancer imaging and photothermal therapy

H Zhou, X Zeng, A Li, W Zhou, L Tang, W Hu… - Nature …, 2020 - nature.com
NIR-II fluorophores have shown great promise for biomedical applications with superior in
vivo optical properties. To date, few small-molecule NIR-II fluorophores have been …

Fluorescent probes for sensing and imaging within specific cellular organelles

H Zhu, J Fan, J Du, X Peng - Accounts of chemical research, 2016 - ACS Publications
Conspectus Fluorescent probes have become powerful tools in biosensing and bioimaging
because of their high sensitivity, specificity, fast response, and technical simplicity. In the last …

Synthesis and application of coumarin fluorescence probes

X Sun, T Liu, J Sun, X Wang - RSC advances, 2020 - pubs.rsc.org
In recent years, the research on fluorescent probes has developed rapidly. Coumarin
fluorescent probes have also been one of the hot topics in recent years. For the synthesis …

Recent progresses in fluorescent probes for detection of polarity

H **ao, P Li, B Tang - Coordination Chemistry Reviews, 2021 - Elsevier
Polarity, as a complex parameter, plays pivotal roles in chemistry and biology. Deviant
polarity change in different subcellular compartments is closely connected with diseases …

Dual emission: classes, mechanisms, and conditions

SK Behera, SY Park… - Angewandte Chemie …, 2021 - Wiley Online Library
There has been much interest in dual‐emission materials in the past few years for materials
and life science applications; however, a systematic overview of the underlying processes is …

A review on methods for diagnosis of breast cancer cells and tissues

Z He, Z Chen, M Tan, S Elingarami, Y Liu, T Li… - Cell …, 2020 - Wiley Online Library
Breast cancer has seriously been threatening physical and mental health of women in the
world, and its morbidity and mortality also show clearly upward trend in China over time …

Photoacoustic imaging-trackable magnetic microswimmers for pathogenic bacterial infection treatment

L **e, X Pang, X Yan, Q Dai, H Lin, J Ye, Y Cheng… - ACS …, 2020 - ACS Publications
Micro/nanorobots have been extensively explored as a tetherless small-scale robotic
biodevice to perform minimally invasive interventions in hard-to-reach regions. Despite the …