The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms

R Alaggio, C Amador, I Anagnostopoulos, AD Attygalle… - Leukemia, 2022 - nature.com
We herein present an overview of the upcoming 5th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …

The tumour microenvironment in B cell lymphomas

DW Scott, RD Gascoyne - Nature Reviews Cancer, 2014 - nature.com
B cell lymphomas are cancers that arise from cells that depend on numerous highly
orchestrated interactions with immune and stromal cells in the course of normal …

Targetable genetic features of primary testicular and primary central nervous system lymphomas

B Chapuy, MGM Roemer, C Stewart… - Blood, The Journal …, 2016 - ashpublications.org
Primary central nervous system lymphomas (PCNSLs) and primary testicular lymphomas
(PTLs) are extranodal large B-cell lymphomas (LBCLs) with inferior responses to current …

The genomic and transcriptional landscape of primary central nervous system lymphoma

J Radke, N Ishaque, R Koll, Z Gu, E Schumann… - Nature …, 2022 - nature.com
Primary lymphomas of the central nervous system (PCNSL) are mainly diffuse large B-cell
lymphomas (DLBCLs) confined to the central nervous system (CNS). Molecular drivers of …

Analysis of the coding genome of diffuse large B-cell lymphoma

L Pasqualucci, V Trifonov, G Fabbri, J Ma, D Rossi… - Nature …, 2011 - nature.com
Diffuse large B-cell lymphoma (DLBCL) is the most common form of human lymphoma.
Although a number of structural alterations have been associated with the pathogenesis of …

The immune landscape and response to immune checkpoint blockade therapy in lymphoma

J Kline, J Godfrey, SM Ansell - Blood, The Journal of the …, 2020 - ashpublications.org
The clinical development of effective cancer immunotherapies, along with advances in
genomic analysis, has led to the identification of tumor environmental features that predict …

Combined genetic inactivation of β2-Microglobulin and CD58 reveals frequent escape from immune recognition in diffuse large B cell lymphoma

M Challa-Malladi, YK Lieu, O Califano, AB Holmes… - Cancer cell, 2011 - cell.com
We report that diffuse large B cell lymphoma (DLBCL) commonly fails to express cell-surface
molecules necessary for the recognition of tumor cells by immune-effector cells. In 29% of …

EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity

MK Gandhi, T Hoang, SC Law, S Brosda… - Blood, The Journal …, 2021 - ashpublications.org
Primary central nervous system lymphoma (PCNSL) is confined to the brain, eyes, and
cerebrospinal fluid without evidence of systemic spread. Rarely, PCNSL occurs in the …

Patterns of outcome and prognostic factors in primary large-cell lymphoma of the testis in a survey by the International Extranodal Lymphoma Study Group

E Zucca, A Conconi, TI Mughal, AH Sarris… - Journal of Clinical …, 2003 - ascopubs.org
Purpose: To determine clinical features and patterns of outcome of primary testicular diffuse
large B-cell lymphomas (DLCL). Patients and Methods: A retrospective international survey …

The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing

I Vater, M Montesinos-Rongen, M Schlesner, A Haake… - Leukemia, 2015 - nature.com
To decipher the mutational pattern of primary CNS lymphoma (PCNSL), we performed
whole-exome sequencing to a median coverage of 103× followed by mutation verification in …