Double-stranded RNA has been shown to induce gene silencing in diverse eukaryotes and
by a variety of pathways. We have examined the taxonomic distribution and the phylogenetic …

Filamentous fungi are widely used in biotechnology as cell factories for the production of
chemicals, pharmaceuticals and enzymes. In order to improve their productivities, genetic …

Small RNA (sRNA)-mediated trans-kingdom RNA interference (RNAi) between host and
pathogen has been demonstrated and utilized. However, interspecies RNAi in rhizospheric …

Our duty to conserve global natural ecosystems is increasingly in conflict with our need to
feed an expanding population. The use of conventional pesticides not only damages the …

The initial focus of recombinant protein production by filamentous fungi related to exploiting
the extraordinary extracellular enzyme synthesis and secretion machinery of industrial …

RNA silencing (or RNA interference, RNAi) is a conserved mechanism for regulating gene
expression in eukaryotes. The discovery of natural trans‐kingdom RNAi indicated that small …

Filamentous fungi have long been used for production of a range of valuable products; with
the advent of molecular biology, it became apparent that these fungi possess considerable …

RNA interference (RNAi) is a conserved eukaryotic gene regulatory mechanism that uses
small noncoding RNAs to mediate posttranscriptional/transcriptional gene silencing. The …

Small RNA molecules of about 20 to 30 nucleotides function in gene regulation and
genomic defense via conserved eukaryotic RNA interference (RNAi)-related pathways. The …

Filamentous fungi have a long-standing tradition as industrial producers of primary and
secondary metabolites. Initially, industrial scientists selected production strains from natural …