Breast cancer precursors revisited: molecular features and progression pathways

MA Lopez‐Garcia, FC Geyer, M Lacroix‐Triki… - …, 2010 - Wiley Online Library
Lopez‐Garcia MA, Geyer FC, Lacroix‐Triki M, Marchió C & Reis‐Filho JS (2010)
Histopathology 57, 171–192 Breast cancer precursors revisited: molecular features and …

Lobular carcinoma in situ

HY Wen, E Brogi - Surgical pathology clinics, 2018 - Elsevier
Lobular carcinoma in situ (LCIS) is a risk factor and a nonobligate precursor of breast
carcinoma. The relative risk of invasive carcinoma after classic LCIS diagnosis is …

FGFR1 Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas

JS Reis-Filho, PT Simpson, NC Turner… - Clinical Cancer …, 2006 - aacrjournals.org
Purpose: Classic lobular carcinomas (CLC) account for 10% to 15% of all breast cancers. At
the genetic level, CLCs show recurrent physical loss of chromosome16q coupled with the …

Lobular breast cancer: Clinical, molecular and morphological characteristics

M Christgen, D Steinemann, E Kühnle, F Länger… - … -Research and Practice, 2016 - Elsevier
Infiltrating lobular breast cancer (ILBC) is the most common special breast cancer subtype.
This review provides a comprehensive description of ILBC characteristics, including …

High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular …

TMA Abdel-Fatah, DG Powe, Z Hodi… - The American journal …, 2007 - journals.lww.com
This study was undertaken to determine the morphologic features and frequency of putative
precursor lesions involved in the development of some pure forms of special types and low …

Lobular neoplasia of the breast revisited with emphasis on the role of E-cadherin immunohistochemistry

DJ Dabbs, SJ Schnitt, FC Geyer, B Weigelt… - The American journal …, 2013 - journals.lww.com
Lobular neoplasia (LN) is a term that encompasses both lobular carcinoma in situ and
atypical lobular hyperplasia. These lesions have been shown to constitute both risk …

Genomic and mutational profiling to assess clonal relationships between multiple non–small cell lung cancers

N Girard, I Ostrovnaya, C Lau, B Park… - Clinical cancer …, 2009 - aacrjournals.org
Purpose: In cases of multiple non–small cell lung cancer, clinicians must decide whether
patients have independent tumors or metastases and tailor treatment accordingly. Decisions …

Aberrant expression of E-cadherin in lobular carcinomas of the breast

L Da Silva, S Parry, L Reid, P Keith… - The American journal …, 2008 - journals.lww.com
Invasive lobular carcinoma (ILC) and lobular carcinoma in situ characteristically show loss of
E-cadherin expression and so immunohistochemistry for E-cadherin is being increasingly …

Lobular breast carcinoma and its variants

EA Rakha, IO Ellis - Seminars in diagnostic pathology, 2010 - Elsevier
Lobular carcinoma is a special type of breast cancer that shows distinct clinical presentation,
morphologic and molecular features, and clinical behavior, and its incidence is rising in …

Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

PT Simpson, JS Reis‐Filho… - The Journal of …, 2008 - Wiley Online Library
Pleomorphic lobular carcinomas (PLC) of the breast display histological features associated
with classic invasive lobular carcinoma (ILC), yet they also exhibit more conspicuous …