Sex differences in the neural mechanisms mediating addiction: a new synthesis and hypothesis

JB Becker, AN Perry, C Westenbroek - Biology of sex differences, 2012 - Springer
In this review we propose that there are sex differences in how men and women enter onto
the path that can lead to addiction. Males are more likely than females to engage in risky …

Monoamine oxidase inhibitors, and iron chelators in depressive illness and neurodegenerative diseases

MBH Youdim - Journal of Neural Transmission, 2018 - Springer
In early 1920s, tyramine oxidase was discovered that metabolized tyramine and in 1933
Blaschko demonstrated that this enzyme also metabolized adrenaline, noradrenaline and …

Sex Differences in the Striatal Dopamine D2 Receptor Binding Characteristics in Vivo

T Pohjalainen, JO Rinne, K Någren… - American Journal of …, 1998 - Am Psychiatric Assoc
OBJECTIVE: The authors investigated whether striatal dopamine D2 receptor binding
characteristics in vivo are similar in men and women and whether there are sex-related …

Changes in sensorimotor inhibition across the menstrual cycle: implications for neuropsychiatric disorders

NR Swerdlow, PL Hartman, PP Auerbach - Biological psychiatry, 1997 - Elsevier
The startle reflex is inhibited when the startling noise is preceded 30–500 msec by a weak
prepulse.“Prepulse inhibition”(PPI) is reduced in specific neuropsychiatric disorders …

Biochemical and molecular studies using human autopsy brain tissue

MR Hynd, JM Lewohl, HL Scott… - Journal of …, 2003 - Wiley Online Library
The use of human brain tissue obtained at autopsy for neurochemical, pharmacological and
physiological analyses is reviewed. RNA and protein samples have been found suitable for …

Dose-and sex-dependent effects of the neurotoxin 6-hydroxydopamine on the nigrostriatal dopaminergic pathway of adult rats: differential actions of estrogen in males …

HE Murray, AV Pillai, SR McArthur, N Razvi, KP Datla… - Neuroscience, 2003 - Elsevier
Epidemiological and clinical studies provide growing evidence for marked sex differences in
the incidence of certain neurological disorders that are largely attributed to the …

Sex differences in brain anatomy

E Luders, AW Toga - Progress in brain research, 2010 - Elsevier
Over the past decades scientific studies have revealed a number of striking sex differences
in the human brain. This chapter highlights some of the most important discoveries with …

Modeling sporadic Alzheimer's disease: the insulin resistant brain state generates multiple long-term morphobiological abnormalities including hyperphosphorylated …

M Salkovic-Petrisic, J Osmanovic… - Journal of …, 2009 - content.iospress.com
Nosologically, Alzheimer's disease (AD) is not a single disorder. Missense gene mutations
involved in increased formation of the amyloid-β protein precursor derivatives amyloid-β …

Reduced dopamine turnover in the basal ganglia of depressed suicides

C Bowden, SC Cheetham, S Lowther, CLE Katona… - Brain research, 1997 - Elsevier
We have measured the concentrations of dopamine, and the dopamine metabolites
homovanillic acid (HVA) and dihydroxyphenylacetic acid (DOPAC), in five brain regions from …

Determination of serotonin and dopamine metabolites in human brain microdialysis and cerebrospinal fluid samples by UPLC-MS/MS: discovery of intact glucuronide …

T Suominen, P Uutela, RA Ketola, J Bergquist… - PLoS …, 2013 - journals.plos.org
An UPLC-MS/MS method was developed for the determination of serotonin (5-HT),
dopamine (DA), their phase I metabolites 5-HIAA, DOPAC and HVA, and their sulfate and …