Thiamine, also known as vitamin B1, is an essential nutrient that plays a crucial role in
energy metabolism and overall health. It is a water-soluble vitamin that plays an important …

Thiamine (vitamin B1) is essential for brain function because of the coenzyme role of
thiamine diphosphate (ThDP) in glucose and energy metabolism. In order to compensate …

Septic shock is associated with unacceptably high mortality rates, mainly in develo**
countries. New adjunctive therapies have been explored to reduce global mortality related to …

One of the serious complications of diabetes mellitus is diabetic nephropathy (DN) which
may finally lead to renal failure. The current study aimed to explore the effect of …

The prevalence of testicular dysfunction is increasing as it is a common diabetes mellites
(DM) complication. The objective of this study is to explore the potential protective effect of …

Thiamine precursors, the most studied being benfotiamine (BFT), have protective effects in
mouse models of neurodegenerative diseases. BFT decreased oxidative stress and …

Thiamine (vitamin B1) is essential for the brain. This is attributed to the coenzyme role of
thiamine diphosphate (ThDP) in glucose and energy metabolism. The synthetic thiamine …

Abstract Thiamine (vitamin B1), under the proper conditions, is able to reversibly open the
thiazole ring, forming a thiol‐bearing molecule that can be further oxidized to the …

Background: Cardiac arrest (CA) can lead to neuronal degeneration and death through
various pathways, including oxidative, inflammatory, and metabolic stress. However, current …

There has been increased interest in the synthesis of benfotiamine during the past few
years, most likely as a direct consequence of growing market demand. It has much higher …