Systems strategies for develo** industrial microbial strains

SY Lee, HU Kim - Nature biotechnology, 2015 - nature.com
Industrial strain development requires system-wide engineering and optimization of cellular
metabolism while considering industrially relevant fermentation and recovery processes. It …

Biorefineries for the production of top building block chemicals and their derivatives

S Choi, CW Song, JH Shin, SY Lee - Metabolic engineering, 2015 - Elsevier
Due to the growing concerns on the climate change and sustainability on petrochemical
resources, DOE selected and announced the bio-based top 12 building blocks and …

Bio-based production of monomers and polymers by metabolically engineered microorganisms

H Chung, JE Yang, JY Ha, TU Chae, JH Shin… - Current opinion in …, 2015 - Elsevier
Highlights•Bio-based production of chemicals is becoming increasingly important.•Metabolic
engineering allows enhanced production of monomers and polymers.•Diamines …

Type II methanotrophs: A promising microbial cell-factory platform for bioconversion of methane to chemicals

DTN Nguyen, OK Lee, TT Nguyen, EY Lee - Biotechnology Advances, 2021 - Elsevier
Methane, the predominant element in natural gas and biogas, represents a promising
alternative to carbon feedstocks in the biotechnological industry due to its low cost and high …

[HTML][HTML] The effects of soybean storage under controlled atmosphere at different temperatures on lipid oxidation and volatile compounds profile

V Ludwig, MRP Berghetti, SR Ribeiro… - Food Research …, 2021 - Elsevier
This study aimed to evaluate the effects of low oxygen partial pressure (pO 2) and high
carbon dioxide partial pressure (pCO 2) combined with different temperatures on the oil …

Microbial engineering for the production of C 2–C 6 organic acids

Y Li, S Yang, D Ma, W Song, C Gao, L Liu… - Natural Product …, 2021 - pubs.rsc.org
Covering: up to the end of 2020 Organic acids, as building block compounds, have been
widely used in food, pharmaceutical, plastic, and chemical industries. Until now, chemical …

Biobased production of succinic acid and its derivatives using metabolically engineered microorganisms

JY Kim, JA Lee, SY Lee - Industrial Biotechnology, 2023 - liebertpub.com
As concerns over climate crisis and environmental issues continue to mount, there is an
urgent need to transition towards a more sustainable society. One key aspect of this …

High-level succinic acid production by overexpressing a magnesium transporter in Mannheimia succiniciproducens

JY Kim, JA Lee, JH Ahn, SY Lee - Proceedings of the National Academy of …, 2024 - pnas.org
Succinic acid (SA), a dicarboxylic acid of industrial importance, can be efficiently produced
by metabolically engineered Mannheimia succiniciproducens. Although the importance of …

Organic acids: succinic and malic acids

JW Lee, MS Han, S Choi, J Yi, TW Lee… - Industrial Biotechnology …, 2011 - pure.kaist.ac.kr
Succinic and malic acids and their derivatives are commonly used chemicals and are
closely associated with our everyday life in the forms of food ingredients, acidulants …

Systematic engineering of TCA cycle for optimal production of a four-carbon platform chemical 4-hydroxybutyric acid in Escherichia coli

S Choi, HU Kim, TY Kim, SY Lee - Metabolic engineering, 2016 - Elsevier
To address climate change and environmental problems, it is becoming increasingly
important to establish biorefineries for the production of chemicals from renewable non-food …