Histone H4 and the maintenance of genome integrity.
PC Megee, BA Morgan, MM Smith - Genes & development, 1995 - genesdev.cshlp.org
The normal progression of Saccharomyces cerevisiae through nuclear division requires the
function of the amino-terminal domain of histone H4. Mutations that delete the domain, or …
function of the amino-terminal domain of histone H4. Mutations that delete the domain, or …
Reconstitution of hyperacetylated, DNase I-sensitive chromatin characterized by high conformational flexibility of nucleosomal DNA
Increased acetylation at specific N-terminal lysines of core histones is a hallmark of active
chromatin in vivo, yet the structural consequences of acetylation leading to increased gene …
chromatin in vivo, yet the structural consequences of acetylation leading to increased gene …
[HTML][HTML] Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region
Abstract Changes in histone acetylation at promoters correlate with transcriptional activation
and repression, but whether acetylation of histones in the coding region of genes is …
and repression, but whether acetylation of histones in the coding region of genes is …
Chromatin compaction at the mononucleosome level
Using a previously described FRET technique, we measured the distance between the ends
of DNA fragments on which nucleosomes were reconstituted from recombinant and native …
of DNA fragments on which nucleosomes were reconstituted from recombinant and native …
Involvement of histone hyperacetylation in triggering DNA fragmentation of rat thymocytes undergoing apoptosis
E Lee, T Furukubo, T Miyabe, A Yamauchi, K Kariya - FEBS letters, 1996 - Elsevier
The treatment of rat thymocytes with trichostatin A and sodium butyrate, which are inhibitors
of histone deacetylase, resulted in an increase in DNA fragmentation in a concentration …
of histone deacetylase, resulted in an increase in DNA fragmentation in a concentration …
Su(Hw) primes 66D and 7F Drosophila chorion genes loci for amplification through chromatin decondensation
Abstract Suppressor of Hairy wing [Su (Hw)] is an insulator protein that participates in
regulating chromatin architecture and gene repression in Drosophila. In previous studies we …
regulating chromatin architecture and gene repression in Drosophila. In previous studies we …
Modulation of the higher-order folding of chromatin by deletion of histone H3 and H4 terminal domains
The 'tails' of histones H3 and H4 were removed by light in situ trypsin digestion of the nuclei.
The alterations in the higher-order folding of chromatin resulting from this treatment were …
The alterations in the higher-order folding of chromatin resulting from this treatment were …
Involvement of histone phosphorylation in apoptosis of human astrocytes after exposure to saline solution
R Enomoto, H Tatsuoka, T Komai, C Sugahara… - Neurochemistry …, 2004 - Elsevier
We have previously found using inhibitors of protein phosphatase that phosphorylation of
histones may be involved in thymocyte apoptosis. In this study, we examined whether …
histones may be involved in thymocyte apoptosis. In this study, we examined whether …
Histone hyperacetylation facilitates chromatin remodelling in a Drosophila embryo cell-free system
WA Krajewski - Molecular and General Genetics MGG, 2000 - Springer
We found that Drosophila embryo extract contains a protein activity (or activities) that can
destabilize nucleosomes, resulting in increased sensitivity to DNase I, release of …
destabilize nucleosomes, resulting in increased sensitivity to DNase I, release of …
Effect of in vivo Histone Hyperacetylation on the State of Chromatin Fibers
WA Krajewski - Journal of Biomolecular Structure and Dynamics, 1999 - Taylor & Francis
We evaluated the contribution of in vivo histone acetylation to the folding of chromatin into its
higher-order structures. We have compared high-order folding patterns of hyperacetylat-ed …
higher-order structures. We have compared high-order folding patterns of hyperacetylat-ed …