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Multiple sclerosis and cognition: synaptic failure and network dysfunction
M Di Filippo, E Portaccio, A Mancini… - Nature Reviews …, 2018 - nature.com
Cognitive impairment is increasingly recognized to be a core feature of multiple sclerosis
(MS), with important implications for the everyday life of individuals with MS and for disease …
(MS), with important implications for the everyday life of individuals with MS and for disease …
Interplay between age and neuroinflammation in multiple sclerosis: effects on motor and cognitive functions
A Musella, A Gentile, FR Rizzo, F De Vito… - Frontiers in aging …, 2018 - frontiersin.org
Aging is one of the main risk factors for the development of many neurodegenerative
diseases. Emerging evidence has acknowledged neuroinflammation as potential trigger of …
diseases. Emerging evidence has acknowledged neuroinflammation as potential trigger of …
Structural plasticity of the hippocampus in neurodegenerative diseases
PDE Weerasinghe-Mudiyanselage, MJ Ang… - International journal of …, 2022 - mdpi.com
Neuroplasticity is the capacity of neural networks in the brain to alter through development
and rearrangement. It can be classified as structural and functional plasticity. The …
and rearrangement. It can be classified as structural and functional plasticity. The …
Multiple immune-inflammatory and oxidative and nitrosative stress pathways explain the frequent presence of depression in multiple sclerosis
G Morris, EMV Reiche, A Murru, AF Carvalho… - Molecular …, 2018 - Springer
Patients with a diagnosis of multiple sclerosis (MS) or major depressive disorder (MDD)
share a wide array of biological abnormalities which are increasingly considered to play a …
share a wide array of biological abnormalities which are increasingly considered to play a …
Cytokines, synaptic plasticity and network dynamics: a matter of balance
L Bellingacci, J Canonichesi, A Mancini… - Neural Regeneration …, 2023 - journals.lww.com
The modern view of the immune system as a sensitizing and modulating machinery of the
central nervous system is now well recognized. However, the specific mechanisms …
central nervous system is now well recognized. However, the specific mechanisms …
Neuroinflammation in Alzheimer's disease: pleiotropic roles for cytokines and neuronal pentraxins
A Swanson, T Wolf, A Sitzmann, AA Willette - Behavioural brain research, 2018 - Elsevier
Neuroinflammation is a potential factor speculated to underlie Alzheimer's disease (AD)
etiopathogenesis and progression. The overwhelming focus in this area of research to date …
etiopathogenesis and progression. The overwhelming focus in this area of research to date …
Basic mechanisms of plasticity and learning
The last century was characterized by a significant scientific effort aimed at unveiling the
neurobiological basis of learning and memory. Thanks to the characterization of the …
neurobiological basis of learning and memory. Thanks to the characterization of the …
Neuro-immune cross-talk in the striatum: from basal ganglia physiology to circuit dysfunction
The basal ganglia network is represented by an interconnected group of subcortical nuclei
traditionally thought to play a crucial role in motor learning and movement execution. During …
traditionally thought to play a crucial role in motor learning and movement execution. During …
Early chronic systemic inflammation and associations with cognitive performance after moderate to severe TBI
Background Cognitive dysfunction adversely effects multiple functional outcomes and social
roles after TBI. We hypothesize that chronic systemic inflammation exacerbates cognitive …
roles after TBI. We hypothesize that chronic systemic inflammation exacerbates cognitive …
Sex differences in olfactory cortex neuronal loss in aging
MM Alotaibi, M De Marco, A Venneri - Frontiers in Human …, 2023 - frontiersin.org
Introduction Aging plays a major role in neurodegenerative disorders such as Alzheimer's
disease, and impacts neuronal loss. Olfactory dysfunction can be an early alteration …
disease, and impacts neuronal loss. Olfactory dysfunction can be an early alteration …