Paleoproteomics

C Warinner, K Korzow Richter, MJ Collins - Chemical reviews, 2022 - ACS Publications
Paleoproteomics, the study of ancient proteins, is a rapidly growing field at the intersection of
molecular biology, paleontology, archaeology, paleoecology, and history. Paleoproteomics …

Bayesian molecular clock dating of species divergences in the genomics era

M Dos Reis, PCJ Donoghue, Z Yang - Nature Reviews Genetics, 2016 - nature.com
Five decades have passed since the proposal of the molecular clock hypothesis, which
states that the rate of evolution at the molecular level is constant through time and among …

A 2-million-year-old ecosystem in Greenland uncovered by environmental DNA

KH Kjær, M Winther Pedersen, B De Sanctis… - Nature, 2022 - nature.com
Abstract Late Pliocene and Early Pleistocene epochs 3.6 to 0.8 million years ago had
climates resembling those forecasted under future warming. Palaeoclimatic records show …

Late Quaternary dynamics of Arctic biota from ancient environmental genomics

Y Wang, MW Pedersen, IG Alsos, B De Sanctis… - Nature, 2021 - nature.com
During the last glacial–interglacial cycle, Arctic biotas experienced substantial climatic
changes, yet the nature, extent and rate of their responses are not fully understood …

A guide to ancient protein studies

J Hendy, F Welker, B Demarchi, C Speller… - Nature ecology & …, 2018 - nature.com
Palaeoproteomics is an emerging neologism used to describe the application of mass
spectrometry-based approaches to the study of ancient proteomes. As with palaeogenomics …

Protein sequences bound to mineral surfaces persist into deep time

B Demarchi, S Hall, T Roncal-Herrero, CL Freeman… - elife, 2016 - elifesciences.org
Proteins persist longer in the fossil record than DNA, but the longevity, survival mechanisms
and substrates remain contested. Here, we demonstrate the role of mineral binding in …

Collagen constitutes about 12% in females and 17% in males of the total protein in mice

K Tarnutzer, D Siva Sankar, J Dengjel, CY Ewald - Scientific Reports, 2023 - nature.com
Collagen has been postulated to be the most abundant protein in our body, making up one-
third of the total protein content in mammals. However, a direct assessment of the total …

Pliocene warmth, polar amplification, and stepped Pleistocene cooling recorded in NE Arctic Russia

J Brigham-Grette, M Melles, P Minyuk, A Andreev… - Science, 2013 - science.org
Understanding the evolution of Arctic polar climate from the protracted warmth of the middle
Pliocene into the earliest glacial cycles in the Northern Hemisphere has been hindered by …

Identification of a new hominin bone from Denisova Cave, Siberia using collagen fingerprinting and mitochondrial DNA analysis

S Brown, T Higham, V Slon, S Pääbo, M Meyer… - Scientific reports, 2016 - nature.com
DNA sequencing has revolutionised our understanding of archaic humans during the Middle
and Upper Palaeolithic. Unfortunately, while many Palaeolithic sites contain large numbers …

Palaeoproteomics resolves sloth relationships

S Presslee, GJ Slater, F Pujos, AM Forasiepi… - Nature ecology & …, 2019 - nature.com
The living tree sloths Choloepus and Bradypus are the only remaining members of Folivora,
a major xenarthran radiation that occupied a wide range of habitats in many parts of the …