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Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling
Cell therapies offer a tailorable, personalized treatment for use in tissue engineering to
address defects arising from trauma, inefficient wound repair, or congenital malformation …
address defects arising from trauma, inefficient wound repair, or congenital malformation …
Engineered biomaterials to guide spheroid formation, function, and fabrication into 3D tissue constructs
Cellular spheroids are aggregates of cells that are being explored to address fundamental
biological questions and as building blocks for engineered tissues. Spheroids possess …
biological questions and as building blocks for engineered tissues. Spheroids possess …
Gelatin methacryloyl hydrogel, from standardization, performance, to biomedical application
J He, Y Sun, Q Gao, C He, K Yao… - Advanced …, 2023 - Wiley Online Library
Gelatin methacryloyl (GelMA), a photocurable hydrogel, is widely used in 3D culture,
particularly in 3D bioprinting, due to its high biocompatibility, tunable physicochemical …
particularly in 3D bioprinting, due to its high biocompatibility, tunable physicochemical …
3D-biofabricated chondrocyte-laden decellularized extracellular matrix-contained gelatin methacrylate auxetic scaffolds under cyclic tensile stimulation for cartilage …
Abstract Three-dimensional (3D) hydrogel constructs can mimic features of the extracellular
matrix (ECM) and have tailorable physicochemical properties to support and maintain the …
matrix (ECM) and have tailorable physicochemical properties to support and maintain the …
Enhanced hepatotoxicity assessment through encapsulated HepG2 spheroids in gelatin hydrogel matrices: Bridging the gap from 2D to 3D culture
Conventional 2D drug screening often fails to accurately predict clinical outcomes. We
present an innovative approach to improve hepatotoxicity assessment by encapsulating …
present an innovative approach to improve hepatotoxicity assessment by encapsulating …
3D bioprinted scaffolds based on functionalized gelatin for soft tissue engineering
Abstract 3D bioprinting application in the medical field requires optimized and adapted
bioinks/biomaterials, along with processing as scaffolds with morphology and structure that …
bioinks/biomaterials, along with processing as scaffolds with morphology and structure that …
Microfluidics single-cell encapsulation reveals that poly-l-lysine-mediated stem cell adhesion to alginate microgels is crucial for cell-cell crosstalk and its self-renewal
Microfluidic cell encapsulation has provided a platform for studying the behavior of
individual cells and has become a turning point in single-cell analysis during the last …
individual cells and has become a turning point in single-cell analysis during the last …
[HTML][HTML] 3D bioprinted GelMA platform for the production of lung tumor spheroids
The study proposes a platform for the formation and culture of non-small cell lung cancer
(NSCLC) spheroids, to obtain an in vitro model suitable for drug and therapy testing. To …
(NSCLC) spheroids, to obtain an in vitro model suitable for drug and therapy testing. To …
Free radical-scavenging composite gelatin methacryloyl hydrogels for cell encapsulation
Gelatin methacryloyl (GelMA) hydrogels have been widely used for cell encapsulation in
tissue engineering due to their cell adhesiveness and biocompatibility. However, free …
tissue engineering due to their cell adhesiveness and biocompatibility. However, free …
[HTML][HTML] In vitro vascularization of 3D cell aggregates in microwells with integrated vascular beds
Most human tissues possess vascular networks supplying oxygen and nutrients.
Engineering of functional tissue and organ models or equivalents often require the …
Engineering of functional tissue and organ models or equivalents often require the …