Near-infrared probes for biothiols (cysteine, homocysteine, and glutathione): A comprehensive review

R Kaushik, N Nehra, V Novakova, P Zimcik - Acs Omega, 2022‏ - ACS Publications
Biothiols (cysteine, homocysteine, and glutathione) are an important class of compounds
with a free thiol group. These biothiols plays an important role in several metabolic …

1, 2, 3-Triazoles of 8-hydroxyquinoline and HBT: Synthesis and studies (DNA binding, antimicrobial, molecular docking, ADME, and DFT)

N Nehra, RK Tittal, VD Ghule - ACS omega, 2021‏ - ACS Publications
A new series of 1, 2, 3-triazole hybrids containing either 2-or 4-hydroxyphenyl benzothiazole
(2-or 4-HBT) and naphthalen-1-ol or 8-hydroxyquinoline (8-HQ) was synthesized in high …

Synthesis, structural investigations, DNA/BSA interactions, molecular docking studies, and anticancer activity of a new 1, 4-disubstituted 1, 2, 3-triazole derivative

T Göktürk, E Sakallı Çetin, T Hökelek, H Pekel… - ACS …, 2023‏ - ACS Publications
We report herein a new 1, 2, 3-triazole derivative, namely, 4-((1-(3, 4-dichlorophenyl)-1 H-1,
2, 3-triazol-4-yl) methoxy)-2-hydroxybenzaldehyde, which was synthesized by copper (I) …

Recent progress in the Cu-catalyzed multicomponent synthesis of 1, 4-disubstituted 1, 2, 3-triazoles

A Anand, R Kumar, J Maity… - Synthetic Communications, 2023‏ - Taylor & Francis
Triazoles has emerged as one of the most important N-heterocyclic compounds with a broad
range of pharmacological applications. This class of molecules can accommodate a wide …

Fluorescent 7-azaindole N-linked 1, 2, 3-triazole: synthesis and study of antimicrobial, molecular docking, ADME and DFT properties

K Sharma, RK Tittal, K Lal, RS Mathpati - New Journal of Chemistry, 2023‏ - pubs.rsc.org
Two libraries of biologically essential and fluorescent 7-azaindole N-linked benzyl 1, 2, 3-
triazole (4a–4i) and 7-azaindole N-linked phenyl 1, 2, 3-triazole (4j–4q) hybrids have been …

Synthesis, antifungal studies, molecular docking, ADME and DNA interaction studies of 4-hydroxyphenyl benzothiazole linked 1, 2, 3-triazoles

N Nehra, RK Tittal, DG Vikas, K Lal - Journal of Molecular Structure, 2021‏ - Elsevier
In search of new bioactive 1, 2, 3-triazole hybrids, some 4-hydroxyphenyl benzothiazole (4-
HBT) linked 1, 2, 3-triazole with varying lengths of alkyl spacers were synthesized from …

Fluorescent molecular probe to detect and differentiate Fe3+ from other metal ions

S Kumar, S Gadiyaram, RK Tittal, R Sharma - Journal of Molecular …, 2023‏ - Elsevier
Herein, a novel 5-nitro isophthalate linked bis-triazole as a fluorescent molecular probe, ie, 5-
nitro isophthalic acid bis-(1-phenylcarbamoylmethyl-1H-[1, 2, 3] triazol-4-ylmethyl) ester was …

Ampyrone linked 1, 2, 3-triazole based chemosensor for selective detection of Fe (II and III) ions

B Lal, S Kumar, V Singh, RK Tittal, G Singh… - Inorganic Chemistry …, 2025‏ - Elsevier
A novel chemosensor based on ampyrone linked 1, 2, 3-triazole hybrid was synthesized
successfully via CuAAC reaction for metal ion detection. The probe was evaluated against …

Synthesis and anticancer activity of 3-(1-aryl-5-methyl-1H-1, 2, 3-triazol-4-yl)-1-phenyl-1H-pyrazole-4-carbaldehydes

BF Abdel-Wahab, BM Kariuki, HA Mohamed… - Journal of Molecular …, 2023‏ - Elsevier
The generation of heterocycles containing 1, 2, 3-triazole and pyrazole moieties has been
explored. The synthesis of these heterocycles is of interest because they are components of …

Synthesis, X-ray crystallography, antimicrobial, molecular docking, and DFT study of bis-triazoles linked ampyrone

B Lal, RK Tittal, RS Mathpati, N Nehra, K Lal - Journal of Molecular …, 2023‏ - Elsevier
A new class of bis-triazoles linked with ampyrone molecules was synthesized from
ampyrone-linked bis-alkyne with different benzyl azides under Cu (I)-catalyzed azide-alkyne …