Nrf2 and NF-κB are important regulators of the response to oxidative stress and
inflammation in the body. Previous pharmacological and genetic studies have confirmed …

Formononetin (FMNT) is a secondary metabolite of flavonoids abundant in legumes and
graminaceous plants such as Astragalus mongholicus Bunge [Fabaceae; Astragali radix] …

Liver injury is one of the adverse effects of methotrexate (MTX). Ferulic acid (FA) is an
antioxidant phytochemical that confers hepatoprotective efficacy; however, its effect against …

Highlights•Naringin induced a marked decrease of renal injury markers in MTX-treated
rats.•Naringin protected against redox imbalance of renal tissue in MTX-treated …

Allergic asthma has been considered as a respiratory disorder with pathological features of
airway inflammation and remodeling, which involves oxidative stress. Formononetin (FMT) is …

Nephrotoxicity is a major complication that limits the therapeutic application of cisplatin
(CIS). Oxidative stress and inflammation are implicated in CIS-induced acute kidney injury …

Background Recently, depression has been identified as a prevalent and severe mental
disorder. However, the mechanisms underlying the depression risk remain elusive. The …

Formononetin (FN), a methoxy isoflavone abundant in many plants and herbs, has been
evidently proven to possess multiple medicinal properties. Our study aimed to clarify the …

Formononetin is an isoflavone, found in herbs like Trifolium pratense, which executes a
variety of physiological activities including anti-neurodegenerative effect. However, the …

Moringa Oleifera (MO) is a herbal plant native to South Asia known for its anti-oxidative and
anti-inflammatory properties. This study explored the protective effects of MO leaf extract …