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Biosensors integrated 3D organoid/organ-on-a-chip system: A real-time biomechanical, biophysical, and biochemical monitoring and characterization
As a full-fidelity simulation of human cells, tissues, organs, and even systems at the
microscopic scale, Organ-on-a-Chip (OOC) has significant ethical advantages and …
microscopic scale, Organ-on-a-Chip (OOC) has significant ethical advantages and …
Engineering brain-on-a-chip platforms
The increasing prevalence of neurological and psychiatric diseases, such as Alzheimer
disease and schizophrenia, necessitates the development of new research tools to …
disease and schizophrenia, necessitates the development of new research tools to …
Advancing nerve regeneration: Peripheral nerve injury (PNI) chip empowering high-speed biomaterial and drug screening
Peripheral nerve injuries (PNIs) represent a significant challenge in regenerative medicine,
often leading to long-term functional impairments. In this study, we introduce the peripheral …
often leading to long-term functional impairments. In this study, we introduce the peripheral …
Brain organoids are new tool for drug screening of neurological diseases
JQ Zhou, LH Zeng, CT Li, DH He… - Neural Regeneration …, 2023 - journals.lww.com
At the level of in vitro drug screening, the development of a phenotypic analysis system with
high-content screening at the core provides a strong platform to support high-throughput …
high-content screening at the core provides a strong platform to support high-throughput …
Biosensor integrated brain-on-a-chip platforms: progress and prospects in clinical translation
Because of the brain's complexity, develo** effective treatments for neurological disorders
is a formidable challenge. Research efforts to this end are advancing as in vitro systems …
is a formidable challenge. Research efforts to this end are advancing as in vitro systems …
[HTML][HTML] Advances of 3D Cell Co-Culture Technology Based on Microfluidic Chips
C Li, W He, Y Song, X Zhang, J Sun, Z Zhou - Biosensors, 2024 - mdpi.com
Cell co-culture technology aims to study the communication mechanism between cells and
to better reveal the interactions and regulatory mechanisms involved in processes such as …
to better reveal the interactions and regulatory mechanisms involved in processes such as …
Tailoring Physicochemical Properties of Photothermal Hydrogels Toward Intrinsically Regenerative Therapies
Photothermal hydrogels (PTHs) are considered next‐generation biomaterials as they offer
remotely defined biophysical information of the extracellular milieu. PTHs allow precise and …
remotely defined biophysical information of the extracellular milieu. PTHs allow precise and …
Brain organoid-on-a-chip: A next-generation human brain avatar for recapitulating human brain physiology and pathology
Neurodegenerative diseases and neurodevelopmental disorders have become increasingly
prevalent; however, the development of new pharmaceuticals to treat these diseases has …
prevalent; however, the development of new pharmaceuticals to treat these diseases has …
Overview on microfluidics devices for monitoring brain disorder biomarkers
Neurological disorders are one of the leading causes of disability and death worldwide. The
complexity of the human brain and therefore the significant structural gap between animal …
complexity of the human brain and therefore the significant structural gap between animal …
Brain-on-a-chip: an emerging platform for studying the nanotechnology-biology interface for neurodegenerative disorders
Neurological disorders have for a long time been a global challenge dismissed by drug
companies, especially due to the low efficiency of most therapeutic compounds to cross the …
companies, especially due to the low efficiency of most therapeutic compounds to cross the …