Layer 1 neocortex: Gating and integrating multidimensional signals

S Huang, SJ Wu, G Sansone, LA Ibrahim, G Fishell - Neuron, 2024 - cell.com
Summary Layer 1 (L1) of the neocortex acts as a nexus for the collection and processing of
widespread information. By integrating ascending inputs with extensive top-down activity …

Step by step: cells with multiple functions in cortical circuit assembly

R Cossart, S Garel - Nature Reviews Neuroscience, 2022 - nature.com
It is often thought that the construction of cortical circuits occurs as the result of an elegantly
designed process that unfolds sequentially as an animal develops until adult functional …

[HTML][HTML] A transcriptomic axis predicts state modulation of cortical interneurons

S Bugeon, J Duffield, M Dipoppa, A Ritoux, I Prankerd… - Nature, 2022 - nature.com
Transcriptomics has revealed that cortical inhibitory neurons exhibit a great diversity of fine
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …

Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex

T Chartrand, R Dalley, J Close, NA Goriounova… - Science, 2023 - science.org
Neocortical layer 1 (L1) is a site of convergence between pyramidal-neuron dendrites and
feedback axons where local inhibitory signaling can profoundly shape cortical processing …

Cajal-retzius cells: Recent advances in identity and function

V Elorriaga, A Pierani, F Causeret - Current Opinion in Neurobiology, 2023 - Elsevier
Abstract Cajal-Retzius cells (CRs) are a transient neuronal type of the develo** cerebral
cortex. Over the years, they have been shown or proposed to play important functions in …

Laminar and dorsoventral organization of layer 1 interneuronal microcircuitry in superficial layers of the medial entorhinal cortex

Y Shi, H Cui, X Li, L Chen, C Zhang, X Zhao, X Li… - Cell Reports, 2023 - cell.com
Summary Layer 1 (L1) interneurons (INs) participate in various brain functions by gating
information flow in the neocortex, but their role in the medial entorhinal cortex (MEC) is still …

Developmental Cajal-Retzius cell death contributes to the maturation of layer 1 cortical inhibition and somatosensory processing

A Damilou, L Cai, AÖ Argunşah, S Han… - Nature …, 2024 - nature.com
The role of developmental cell death in the formation of brain circuits is not well understood.
Cajal-Retzius cells constitute a major transient neuronal population in the mammalian …

Development of auditory cortex circuits

M Chang, PO Kanold - Journal of the Association for Research in …, 2021 - Springer
The ability to process and perceive sensory stimuli is an essential function for animals.
Among the sensory modalities, audition is crucial for communication, pleasure, care for the …

[HTML][HTML] Dynamic interplay between thalamic activity and Cajal-Retzius cells regulates the wiring of cortical layer 1

I Genescu, M Aníbal-Martínez, V Kouskoff… - Cell Reports, 2022 - cell.com
Cortical wiring relies on guidepost cells and activity-dependent processes that are thought to
act sequentially. Here, we show that the construction of layer 1 (L1), a main site of top-down …

Heterozygous Dab1 null mutation disrupts neocortical and hippocampal development

T Honda, Y Hirota, K Nakajima - eneuro, 2023 - eneuro.org
Loss-of-function mutations in Reelin and DAB1 signaling pathways disrupt proper neuronal
positioning in the cerebral neocortex and hippocampus, but the underlying molecular …