Monoclonal gammopathies are characterized by the overproduction of monoclonal Ig (MIg)
detectable in the serum or urine resulting from a clonal proliferation of plasma cells or B …

There have been tremendous advances during the last decade in methods for large-scale,
high-throughput data generation and in novel computational approaches to analyze these …

In November 2017, the Kidney Disease: Improving Global Outcomes (KDIGO) initiative
brought a diverse panel of experts in glomerular diseases together to discuss the 2012 …

Over the past 2 decades, scoring systems for multiple glomerular diseases have emerged,
as have consortia of pathologists and nephrologists for the study of glomerular diseases …

Fibrillary glomerulonephritis (FGN) is a rare proliferative form of glomerular disease
characterized by randomly oriented fibrillar deposits with a mean diameter of 20 nm. By …

Fibrillary glomerulonephritis is a glomerular disease historically defined by glomerular
deposition of Congo red–negative, randomly oriented straight fibrils that lack a hollow center …

Results We retrospectively reviewed kidney biopsies from patients diagnosed with fibrillary
GN or suspected fibrillary GN between 1997 and 2017 (n= 266, 65% female, median age …

The mechanisms of tissue damage in kidney amyloidosis are not well described. To
investigate this further, we used laser microdissection-mass spectrometry to identify proteins …

Kidney research is entering an era of 'big data'and molecular omics data can provide
comprehensive insights into the molecular footprints of cells. In contrast to transcriptomics …

Immunotactoid glomerulopathy (ITG) is a rare form of glomerulonephritis for which our
understanding is limited to case reports and small case series. Herein we describe the …