Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

Recent evidence shows that when ischemic stroke (IS) occurs, the BBB would be destructed,
thereby promoting the immune cells to migrate into the brain, suggesting that the immune …

Unrestrained excessive inflammatory responses exacerbate ischemic brain injury and
impede post-stroke brain recovery. CD4+ CD25+ Foxp3+ regulatory T (Treg) cells play …

Stroke is a leading cause of morbidity and mortality worldwide. It inflicts immeasurable
suffering on patients and their loved ones and carries an immense social cost. Efforts to …

Ischemic stroke is a leading cause of disability and death. It imposes a heavy economic
burden on individuals, families and society. The mortality rate of ischemic stroke has …

The aging process is associated with a remodeling of the immune system involving chronic
low-grade inflammation and a gradual decline in the function of the immune system. These …

While inflammation may not be the cause of disease, it is well known that it contributes to
disease pathogenesis across a multitude of peripheral and central nervous system …

The human gastrointestinal tract has an enormous and diverse microbial community, termed
microbiota, that is necessary for the development of the immune system and tissue …

Increasing evidence hints to the central role of neuroinflammation in the development of post‑
stroke depression. Danger signals released in the acute phase of ischemia trigger microglial …

As the average age of the world population increases, more people will face debilitating
aging-associated conditions, including dementia and stroke. Not only does the incidence of …