Transmembrane proteins comprise~ 30% of the mammalian proteome, mediating
metabolism, signalling, transport and many other functions required for cellular life. The …

Biological membranes are key elements for the maintenance of cell architecture and
physiology. Beyond a pure barrier separating the inner space of the cell from the outer, the …

Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy
function as well as the most common pathological conditions of the brain. Demographic …

Cellular plasma membranes are laterally heterogeneous, featuring a variety of distinct
subcompartments that differ in their biophysical properties and composition. A large number …

Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

Liposomes as drug vehicles have advantages, such as payload protection, tunable carrying
capacity and improved biodistribution. However, due to the dysfunction of targeting moieties …

Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Biological membranes are complex and dynamic assemblies of lipids and proteins.
Poikilothermic organisms including bacteria, fungi, reptiles, and fish do not control their body …

The lipid composition of cellular organelles is tailored to suit their specialized tasks. A
fundamental transition in the lipid landscape divides the secretory pathway in early and late …

The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …