MicroRNAs: history, biogenesis, and their evolving role in animal development and disease
M Bhaskaran, M Mohan - Veterinary pathology, 2014 - journals.sagepub.com
The discovery of microRNAs (miRNAs) in 1993 followed by developments and discoveries
in small RNA biology have redefined the biological landscape by significantly altering the …
in small RNA biology have redefined the biological landscape by significantly altering the …
The evolution of gene regulation by transcription factors and microRNAs
K Chen, N Rajewsky - Nature Reviews Genetics, 2007 - nature.com
Abstract Changes in the patterns of gene expression are widely believed to underlie many of
the phenotypic differences within and between species. Although much emphasis has been …
the phenotypic differences within and between species. Although much emphasis has been …
Epigenetic regulator miRNA pattern differences among SARS-CoV, SARS-CoV-2, and SARS-CoV-2 world-wide isolates delineated the mystery behind the epic …
A detailed understanding of the molecular mechanism of SARS-CoV-2 pathogenesis is still
elusive, and there is a need to address its deadly nature and to design effective …
elusive, and there is a need to address its deadly nature and to design effective …
miR2Disease: a manually curated database for microRNA deregulation in human disease
Abstract 'miR2Disease', a manually curated database, aims at providing a comprehensive
resource of microRNA deregulation in various human diseases. The current version of …
resource of microRNA deregulation in various human diseases. The current version of …
[HTML][HTML] Antiviral immunity directed by small RNAs
Plants and invertebrates can protect themselves from viral infection through RNA silencing.
This antiviral immunity involves production of virus-derived small interfering RNAs (viRNAs) …
This antiviral immunity involves production of virus-derived small interfering RNAs (viRNAs) …
MicroRNA-146a feedback inhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2
J Hou, P Wang, L Lin, X Liu, F Ma, H An… - The journal of …, 2009 - journals.aai.org
Upon recognition of viral components by pattern recognition receptors, including TLRs and
retinoic acid-inducible gene I (RIG-I)-like helicases, cells are activated to produce type I IFN …
retinoic acid-inducible gene I (RIG-I)-like helicases, cells are activated to produce type I IFN …
Viruses, microRNAs, and host interactions
RL Skalsky, BR Cullen - Annual review of microbiology, 2010 - annualreviews.org
One of the most significant recent advances in biomedical research has been the discovery
of the∼ 22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …
of the∼ 22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …
On the importance of host microRNAs during viral infection
Every living organism has to constantly face threats from the environment and deal with a
large number of pathogens against which it has to defend itself to survive. Among those …
large number of pathogens against which it has to defend itself to survive. Among those …
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells
M Ceppi, PM Pereira… - Proceedings of the …, 2009 - National Acad Sciences
In response to inflammatory stimulation, dendritic cells (DCs) have a remarkable pattern of
differentiation (maturation) that exhibits specific mechanisms to control immunity. Here, we …
differentiation (maturation) that exhibits specific mechanisms to control immunity. Here, we …
Prediction and analysis of SARS-CoV-2-targeting MicroRNA in human lung epithelium
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus, is
responsible for the coronavirus disease 2019 (COVID-19) pandemic of 2020. Experimental …
responsible for the coronavirus disease 2019 (COVID-19) pandemic of 2020. Experimental …