miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges

S Zhou, J **, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
world. Although considerable progress has been made in the diagnosis, treatment and …

MicroRNA in cardiovascular biology and disease.

A Wojciechowska, A Braniewska… - … in Clinical & …, 2017 - search.ebscohost.com
MicroRNAs (miRNAs) are members of a non-coding RNA family. They act as negative
regulators of protein translation by affecting messenger RNA (mRNA) stability; they …

Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential

TG Martin, MA Juarros, LA Leinwand - Nature Reviews Cardiology, 2023 - nature.com
Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …

Small RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation

S Srinivasan, A Yeri, PS Cheah, A Chung, K Danielson… - Cell, 2019 - cell.com
Poor reproducibility within and across studies arising from lack of knowledge regarding the
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …

Mir-30d regulates cardiac remodeling by intracellular and paracrine signaling

J Li, AM Salvador, G Li, N Valkov, O Ziegler… - Circulation …, 2021 - Am Heart Assoc
Rationale: Previous translational studies implicate plasma extracellular microRNA-30d (miR-
30d) as a biomarker in left ventricular remodeling and clinical outcome in heart failure (HF) …

Non-exosomal and exosomal circulatory microRNAs: which are more valid as biomarkers?

NNSB Nik Mohamed Kamal… - Frontiers in …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are a group of small non-coding RNAs with approximately 19–25
nucleotides that are involved in regulating a range of developmental and physiological …

[HTML][HTML] MicroRNA and cardiovascular diseases

HA Çakmak, M Demir - Balkan medical journal, 2020 - ncbi.nlm.nih.gov
Cardiovascular diseases are one of the most common causes of death in both develo**
and developed countries worldwide. Even though there have been improvements in primary …

MicroRNAs in heart failure: from biomarker to target for therapy

EL Vegter, P van der Meer, LJ de Windt… - European journal of …, 2016 - Wiley Online Library
MicroRNAs (miRNAs) are increasingly recognized to play important roles in cardiovascular
diseases, including heart failure. These small, non‐coding RNAs have been identified in …

The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research

S Das, AB Abdel-Mageed, C Adamidi, PD Adelson… - Cell, 2019 - cell.com
The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

Biomarkers in cardiovascular disease: Statistical assessment and section on key novel heart failure biomarkers

R Dhingra, RS Vasan - Trends in cardiovascular medicine, 2017 - Elsevier
Cardiovascular disease (CVD) is a leading cause of death worldwide and continues to
increase in prevalence compared to previous decades, in part because of the aging of the …