During the last decade, experimental and clinical studies have demonstrated that isolated
acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and …

The right ventricle (RV) provides sustained low-pressure perfusion of the pulmonary
vasculature, but is sensitive to changes in loading conditions and intrinsic contractility …

Trauma is a leading cause of death and morbidity worldwide. Here, we present the analysis
of a longitudinal multi-omic dataset comprising clinical, cytokine, endotheliopathy biomarker …

Context: Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are conditions at
high risk for the development of hypopituitarism. Objective: The objective of the study was to …

Objective: To determine the prevalence, time course, clinical characteristics, and effect of
adrenal insufficiency (AI) after traumatic brain injury (TBI). Design: Prospective intensive …

Background: Traumatic brain injury (TBI) results in a hypermetabolic and hypercatabolic
status in which adequate nutrition support is essential to improve clinical outcome. The …

Major pulmonary disorders may occur after brain injuries as ventilator-associated
pneumonia, acute respiratory distress syndrome or neurogenic pulmonary edema. They are …

Mood disorders, particularly major depression, are the most frequent complication of
traumatic brain injury. Major depression is present in about 40% of patients hospitalization …

Hypogonadism is often observed in the presence of common acute and chronic illnesses in
men. Low testosterone levels in these patients can be associated with loss of lean body …

Deficiency of growth hormone (GH) in adults results in a syndrome characterized by
decreased muscle mass and exercise capacity, increased visceral fat, impaired quality of …