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Molecular pathways of major depressive disorder converge on the synapse
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …
molecular etiology. Extensive studies at different molecular levels point to a high complexity …
[HTML][HTML] Brain–gut–microbiota axis in depression: A historical overview and future directions
Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …
worldwide. Despite abundant research, the precise mechanisms underlying the …
Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity
The gut-brain axis is implicated in depression development, yet its underlying mechanism
remains unclear. We observed depleted gut bacterial species, including Bifidobacterium …
remains unclear. We observed depleted gut bacterial species, including Bifidobacterium …
Gut microbiota changes require vagus nerve integrity to promote depressive-like behaviors in mice
Chronic stress constitutes a major risk factor for depression that can disrupt various aspects
of homeostasis, including the gut microbiome (GM). We have recently shown that GM …
of homeostasis, including the gut microbiome (GM). We have recently shown that GM …
Gut microbiota in anxiety and depression: unveiling the relationships and management options
The gut microbiota is critical for maintaining human health and the immunological system.
Several neuroscientific studies have shown the significance of microbiota in develo** …
Several neuroscientific studies have shown the significance of microbiota in develo** …
Effect of fecal microbiota transplant on symptoms of psychiatric disorders: a systematic review
Abstract Background The Gut-Brain-Axis is a bidirectional signaling pathway between the
gastrointestinal (GI) tract and the brain. The hundreds of trillions of microorganisms …
gastrointestinal (GI) tract and the brain. The hundreds of trillions of microorganisms …
[HTML][HTML] The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches
Depression is the most prevalent mental disorder in the world associated with huge socio-
economic consequences. While depressive-related symptoms are well known, the …
economic consequences. While depressive-related symptoms are well known, the …
The impact of adult neurogenesis on affective functions: of mice and men
In most mammals, new neurons are not only produced during embryogenesis but also after
birth. Soon after adult neurogenesis was discovered, the influence of recruiting new neurons …
birth. Soon after adult neurogenesis was discovered, the influence of recruiting new neurons …
Gut dysbiosis impairs hippocampal plasticity and behaviors by remodeling serum metabolome
G Liu, Q Yu, B Tan, X Ke, C Zhang, H Li, T Zhang… - Gut …, 2022 - Taylor & Francis
Accumulating evidence suggests that gut microbiota as a critical mediator of gut-brain axis
plays an important role in human health. Altered gut microbial profiles have been implicated …
plays an important role in human health. Altered gut microbial profiles have been implicated …
SCFAs supplementation rescues anxiety-and depression-like phenotypes generated by fecal engraftment of treatment-resistant depression rats
Alteration of gut microbiota and microbial metabolites such as short-chain fatty acids
(SCFAs) coexisted with stress-generated brain disorders, including depression. Herein, we …
(SCFAs) coexisted with stress-generated brain disorders, including depression. Herein, we …