Experimental methods for evaluating the bacterial uptake of Trojan horse antibacterials
JW Southwell, CM Black, AK Duhme‐Klair - ChemMedChem, 2021 - Wiley Online Library
The field of antibacterial siderophore conjugates, referred to as Trojan Horse antibacterials,
has received increasing attention in recent years, driven by the rise of antimicrobial …
has received increasing attention in recent years, driven by the rise of antimicrobial …
Iron: Key player in cancer and cell cycle?
Background Iron is an essential element for growth and metabolic activities of all living
organisms but remains in its oxyhydroxide ferric ion form in the surrounding. Unavailability of …
organisms but remains in its oxyhydroxide ferric ion form in the surrounding. Unavailability of …
Manuka honey chelates iron and impacts iron regulation in key bacterial pathogens
Aim The aim of this study was to test the hypothesis that Manuka honey (MH) chelates iron
and promotes an iron‐limiting environment, which contributes to its antimicrobial activity …
and promotes an iron‐limiting environment, which contributes to its antimicrobial activity …
SufT is required for growth of Mycobacterium smegmatis under iron limiting conditions
T Tamuhla, L Joubert, D Willemse… - Microbiology, 2020 - microbiologyresearch.org
Iron-sulphur (FeS) clusters are versatile cofactors required for a range of biological
processes within cells. Due to the reactive nature of the constituent molecules, assembly …
processes within cells. Due to the reactive nature of the constituent molecules, assembly …
Coordination of cell division and chromosome segregation by iron and a sRNA in Escherichia coli
E Ng Kwan Lim, M Grüll, N Larabi, D Lalaouna… - Frontiers in …, 2024 - frontiersin.org
Iron is a vital metal ion frequently present as a cofactor in metabolic enzymes involved in
central carbon metabolism, respiratory chain, and DNA synthesis. Notably, iron starvation …
central carbon metabolism, respiratory chain, and DNA synthesis. Notably, iron starvation …
Genome-wide profiling of Hfq-bound RNAs reveals the iron-responsive small RNA RusT in Caulobacter crescentus
LN Vogt, G Panis, A Schäpers, N Peschek, M Huber… - Mbio, 2024 - Am Soc Microbiol
The alphaproteobacterium Caulobacter crescentus thrives in oligotrophic environments and
is able to optimally exploit minimal resources by entertaining an intricate network of gene …
is able to optimally exploit minimal resources by entertaining an intricate network of gene …
Resistance to Bipyridyls Mediated by the TtgABC Efflux System in Pseudomonas putida KT2440
Resistance-nodulation-division (RND) transporters are involved in antibiotic resistance and
have a broad substrate specificity. However, the physiological significance of these efflux …
have a broad substrate specificity. However, the physiological significance of these efflux …
Immobilized FhuD2 Siderophore-Binding Protein Enables Purification of Salmycin Sideromycins from Streptomyces violaceus DSM 8286
GSM Rivera, CR Beamish… - ACS infectious …, 2018 - ACS Publications
Siderophores are a structurally diverse class of natural products common to most bacteria
and fungi as iron (III)-chelating ligands. Siderophores, including trihydroxamate …
and fungi as iron (III)-chelating ligands. Siderophores, including trihydroxamate …
Imaging‐based profiling for elucidation of antibacterial mechanisms of action
AA Baranova, VA Alferova, VA Korshun… - Biotechnology and …, 2024 - Wiley Online Library
In this review, we aim to summarize experimental data and approaches to identifying cellular
targets or mechanisms of action of antibacterials based on imaging techniques. Imaging …
targets or mechanisms of action of antibacterials based on imaging techniques. Imaging …
Influence of Lactic Acid on Cell Cycle Progressions in Lactobacillus bulgaricus During Batch Culture
S Chen, H Niu, Y Wu, J Sun, X Han, L Zhang - Applied Biochemistry and …, 2021 - Springer
Lactic acid has been proved to inhibit the proliferation of lactic acid bacteria in the
fermentation process. To shed light on the cell cycle alterations in acidic conditions, the cell …
fermentation process. To shed light on the cell cycle alterations in acidic conditions, the cell …